Your browser doesn't support javascript.
loading
Female Human Spines with Simulated Osteolytic Defects: CT-based Structural Analysis of Vertebral Body Strength.
Alkalay, Ron; Adamson, Robert; Miropolsky, Alexander; Hackney, David.
Afiliación
  • Alkalay R; From the Center for Advanced Orthopedic Studies, Department of Orthopedic Surgery (R. Alkalay, R. Adamson, A.M.), and Department of Radiology (D.H.), Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215.
  • Adamson R; From the Center for Advanced Orthopedic Studies, Department of Orthopedic Surgery (R. Alkalay, R. Adamson, A.M.), and Department of Radiology (D.H.), Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215.
  • Miropolsky A; From the Center for Advanced Orthopedic Studies, Department of Orthopedic Surgery (R. Alkalay, R. Adamson, A.M.), and Department of Radiology (D.H.), Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215.
  • Hackney D; From the Center for Advanced Orthopedic Studies, Department of Orthopedic Surgery (R. Alkalay, R. Adamson, A.M.), and Department of Radiology (D.H.), Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215.
Radiology ; 288(2): 436-444, 2018 08.
Article en En | MEDLINE | ID: mdl-29869960
Purpose To evaluate a CT structural analysis protocol (SAP) for estimating the strength of human female cadaveric spines with lytic lesions. Materials and Methods Osteolytic foci was created in the middle vertebra of 44 thoracic and lumbar three-level segments from 11 female cadavers (age range, 50-70 years). The segments underwent CT by using standard clinical protocol and their failure strength was assessed at CT SAP. The spines were mechanically tested to failure in pure axial compression or in compression with torsion. The relationships of defect size, bone mineral density, and predicted failure load (at CT SAP) with measured vertebral strength were assessed with linear regression. Analysis of variance and Tukey test were used to evaluate the effect of region and mechanical test on spine strength. Results With axial compression, CT SAP predictions of vertebral strength correlated with the thoracic (r = 0.84; P < .001) and lumbar (r = 0.85; P < .001) segment-measured strength. Bone mineral density correlated with the lumbar (r = 0.64; P = .003) and thoracic (r, 0.51; P = .050) strength. At compression with torsion, CT SAP predictions of strength were moderately correlated with vertebral strength (r = 0.66; P = .018). At compression with torsion, bone mineral density was not correlated with spinal strength (thoracic and lumbar: r = 0.31 and r = 0.26, respectively; P = .539 and .610, respectively). The lytic focus size (range, 28%-41%) was not associated with vertebral strength. Conclusion CT SAP assessment of strength in vertebrae with lytic lesions correlated with the measured strength of female vertebral bodies. © RSNA, 2018 Online supplemental material is available for this article.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteólisis / Columna Vertebral / Tomografía Computarizada por Rayos X / Fuerza Compresiva Tipo de estudio: Guideline Límite: Aged / Female / Humans / Middle aged Idioma: En Revista: Radiology Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteólisis / Columna Vertebral / Tomografía Computarizada por Rayos X / Fuerza Compresiva Tipo de estudio: Guideline Límite: Aged / Female / Humans / Middle aged Idioma: En Revista: Radiology Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos