Curcumin inhibits autocrine growth hormone-mediated invasion and metastasis by targeting NF-&#954;B signaling and polyamine metabolism in breast cancer cells.

Coker-Gurkan, Ajda; Celik, Merve; Ugur, Merve; Arisan, Elif-Damla; Obakan-Yerlikaya, Pinar; Durdu, Zeynep Begum; Palavan-Unsal, Narcin

Curcumin inhibits autocrine growth hormone-mediated invasion and metastasis by targeting NF-κB signaling and polyamine metabolism in breast cancer cells.

Coker-Gurkan, Ajda; Celik, Merve; Ugur, Merve; Arisan, Elif-Damla; Obakan-Yerlikaya, Pinar; Durdu, Zeynep Begum; Palavan-Unsal, Narcin.

Afiliación

Coker-Gurkan A; Department of Molecular Biology and Genetics, Science and Literature Faculty, Istanbul Kultur University, Atakoy Campus, 34156, Istanbul, Turkey. a.coker@iku.edu.tr.
Celik M; Department of Molecular Biology and Genetics, Science and Literature Faculty, Istanbul Kultur University, Atakoy Campus, 34156, Istanbul, Turkey.
Ugur M; Department of Molecular Biology and Genetics, Science and Literature Faculty, Istanbul Kultur University, Atakoy Campus, 34156, Istanbul, Turkey.
Arisan ED; Department of Molecular Biology and Genetics, Science and Literature Faculty, Istanbul Kultur University, Atakoy Campus, 34156, Istanbul, Turkey.
Obakan-Yerlikaya P; Department of Molecular Biology and Genetics, Science and Literature Faculty, Istanbul Kultur University, Atakoy Campus, 34156, Istanbul, Turkey.
Durdu ZB; Department of Molecular Biology and Genetics, Science and Literature Faculty, Istanbul Kultur University, Atakoy Campus, 34156, Istanbul, Turkey.
Palavan-Unsal N; Department of Molecular Biology and Genetics, Science and Literature Faculty, Istanbul Kultur University, Atakoy Campus, 34156, Istanbul, Turkey.

Amino Acids ; 50(8): 1045-1069, 2018 Aug.

Article en En | MEDLINE | ID: mdl-29770869

Asunto(s)

Antineoplásicos/farmacología; Neoplasias de la Mama/tratamiento farmacológico; Curcumina/farmacología; Hormona de Crecimiento Humana/antagonistas & inhibidores; FN-kappa B/antagonistas & inhibidores; Poliaminas/metabolismo; Antineoplásicos/uso terapéutico; Apoptosis/efectos de los fármacos; Comunicación Autocrina/efectos de los fármacos; Neoplasias de la Mama/metabolismo; Neoplasias de la Mama/patología; Movimiento Celular/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Curcuma/química; Curcumina/uso terapéutico; Transición Epitelial-Mesenquimal/efectos de los fármacos; Femenino; Puntos de Control de la Fase G2 del Ciclo Celular/efectos de los fármacos; Humanos; Puntos de Control de la Fase M del Ciclo Celular/efectos de los fármacos; Células MCF-7; FN-kappa B/metabolismo; Metástasis de la Neoplasia; Extractos Vegetales/farmacología; Extractos Vegetales/uso terapéutico

Palabras clave

Apoptosis; Breast cancer; Curcumin; Growth hormone; NF-κB; Polyamine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poliaminas / Neoplasias de la Mama / FN-kappa B / Hormona de Crecimiento Humana / Curcumina / Antineoplásicos Límite: Female / Humans Idioma: En Revista: Amino Acids Asunto de la revista: BIOQUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Austria

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