The intranuclear PEX domain of MMP involves proliferation, migration, and metastasis of aggressive adenocarcinoma cells.

Okusha, Yuka; Eguchi, Takanori; Sogawa, Chiharu; Okui, Tatsuo; Nakano, Keisuke; Okamoto, Kuniaki; Kozaki, Ken-Ichi

Okusha, Yuka; Eguchi, Takanori; Sogawa, Chiharu; Okui, Tatsuo; Nakano, Keisuke; Okamoto, Kuniaki; Kozaki, Ken-Ichi.

Afiliación

Okusha Y; Department of Dental Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Eguchi T; Department of Dental Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Sogawa C; Advanced Research Center for Oral and Craniofacial Sciences, Graduate School of Medicine, Dentistry andPharmaceutical Sciences, Okayama University, Okayama, Japan.
Okui T; Department of Dental Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Nakano K; Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Okamoto K; Advanced Research Center for Oral and Craniofacial Sciences, Graduate School of Medicine, Dentistry andPharmaceutical Sciences, Okayama University, Okayama, Japan.
Kozaki KI; Department of Pathology and Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.

J Cell Biochem ; 119(9): 7363-7376, 2018 09.

Article en En | MEDLINE | ID: mdl-29761931

Asunto(s)

Adenocarcinoma/patología; Neoplasias del Colon/patología; Hemopexina/metabolismo; Metaloproteinasa 3 de la Matriz/genética; Metaloproteinasa 3 de la Matriz/metabolismo; Metaloproteinasa 9 de la Matriz/genética; Metaloproteinasa 9 de la Matriz/metabolismo; Aloinjertos/metabolismo; Análisis de Varianza; Animales; Línea Celular Tumoral; Movimiento Celular; Proliferación Celular; Expresión Génica; Técnicas de Silenciamiento del Gen; Neoplasias Pulmonares/patología; Ratones; Ratones Endogámicos BALB C; Invasividad Neoplásica; Metástasis de la Neoplasia

Palabras clave

PEX domain; cancer metastasis; non-proteolytic MMP; nuclear MMP; tumor stroma

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemopexina / Adenocarcinoma / Neoplasias del Colon / Metaloproteinasa 3 de la Matriz / Metaloproteinasa 9 de la Matriz Límite: Animals Idioma: En Revista: J Cell Biochem Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

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