Fisetin inhibits the generation of inflammatory mediators in interleukin-1ß-induced human lung epithelial cells by suppressing the NF-&#954;B and ERK1/2 pathways.

Peng, Hui-Ling; Huang, Wen-Chung; Cheng, Shu-Chen; Liou, Chian-Jiun

Fisetin inhibits the generation of inflammatory mediators in interleukin-1ß-induced human lung epithelial cells by suppressing the NF-κB and ERK1/2 pathways.

Peng, Hui-Ling; Huang, Wen-Chung; Cheng, Shu-Chen; Liou, Chian-Jiun.

Afiliación

Peng HL; Graduate Institute of Health Industry Technology, Research Center for Food and Cosmetic Safety, Research Center for Chinese Herbal Medicine, College of Human Ecology, Chang Gung University of Science and Technology, No.261, Wenhua 1st Rd., Guishan Dist., Taoyuan City 33303, Taiwan.
Huang WC; Graduate Institute of Health Industry Technology, Research Center for Food and Cosmetic Safety, Research Center for Chinese Herbal Medicine, College of Human Ecology, Chang Gung University of Science and Technology, No.261, Wenhua 1st Rd., Guishan Dist., Taoyuan City 33303, Taiwan; Division of Aller
Cheng SC; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Liou CJ; Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Linkou, Guishan Dist., Taoyuan City 33303, Taiwan; Department of Nursing, Division of Basic Medical Sciences, Research Center for Chinese Herbal Medicine, Chang Gung University of Science and Techn

Int Immunopharmacol ; 60: 202-210, 2018 Jul.

Article en En | MEDLINE | ID: mdl-29758489

Asunto(s)

Antiinflamatorios/farmacología; Citocinas/metabolismo; Células Epiteliales/efectos de los fármacos; Flavonoides/farmacología; Sistema de Señalización de MAP Quinasas/efectos de los fármacos; FN-kappa B/antagonistas & inhibidores; Células A549; Línea Celular; Ciclooxigenasa 2/genética; Ciclooxigenasa 2/metabolismo; Células Epiteliales/metabolismo; Flavonoles; Hemo-Oxigenasa 1/metabolismo; Humanos; Molécula 1 de Adhesión Intercelular/genética; Molécula 1 de Adhesión Intercelular/metabolismo; Pulmón/citología; Factor 2 Relacionado con NF-E2/metabolismo; FN-kappa B/metabolismo; Transducción de Señal/efectos de los fármacos

Palabras clave

Anti-inflammation; COX-2; ERK1/2; Fisetin; ICAM-1; NF-κB

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Flavonoides / Citocinas / FN-kappa B / Sistema de Señalización de MAP Quinasas / Células Epiteliales / Antiinflamatorios Límite: Humans Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Países Bajos

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