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BCL-2 levels do not predict azathioprine treatment response in inflammatory bowel disease, but inhibition induces lymphocyte apoptosis and ameliorates colitis in mice.
Weder, B; Mozaffari, M; Biedermann, L; Mamie, C; Moncsek, A; Wang, L; Clarke, S H; Rogler, G; McRae, B L; Graff, C L; Ruiz, P A; Hausmann, M.
Afiliación
  • Weder B; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Mozaffari M; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Biedermann L; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Mamie C; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Moncsek A; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Wang L; AbbVie Bioresearch Center, Worcester, MA, USA.
  • Clarke SH; AbbVie Bioresearch Center, Worcester, MA, USA.
  • Rogler G; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • McRae BL; AbbVie Bioresearch Center, Worcester, MA, USA.
  • Graff CL; AbbVie Bioresearch Center, Worcester, MA, USA.
  • Ruiz PA; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Hausmann M; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Clin Exp Immunol ; 193(3): 346-360, 2018 09.
Article en En | MEDLINE | ID: mdl-29745420
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Azatioprina / Linfocitos / Enfermedades Inflamatorias del Intestino / Colitis / Proteínas Proto-Oncogénicas c-bcl-2 Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Clin Exp Immunol Año: 2018 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Azatioprina / Linfocitos / Enfermedades Inflamatorias del Intestino / Colitis / Proteínas Proto-Oncogénicas c-bcl-2 Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Clin Exp Immunol Año: 2018 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido