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Mechanisms of Aerobic Exercise Impairment in Diabetes: A Narrative Review.
Wahl, Matthew P; Scalzo, Rebecca L; Regensteiner, Judith G; Reusch, Jane E B.
Afiliación
  • Wahl MP; Division of Endocrinology, University of Colorado School of Medicine, Aurora, CO, United States.
  • Scalzo RL; Veterans Administration Eastern Colorado Health Care System, Denver, CO, United States.
  • Regensteiner JG; Division of Endocrinology, University of Colorado School of Medicine, Aurora, CO, United States.
  • Reusch JEB; Center for Women's Health Research, Department of Medicine, University of Colorado School of Medicine, Aurora, CO, United States.
Article en En | MEDLINE | ID: mdl-29720965
The prevalence of diabetes in the United States and globally has been rapidly increasing over the last several decades. There are now estimated to be 30.3 million people in the United States and 422 million people worldwide with diabetes. Diabetes is associated with a greatly increased risk of cardiovascular mortality, which is the leading cause of death in adults with diabetes. While exercise training is a cornerstone of diabetes treatment, people with diabetes have well-described aerobic exercise impairments that may create an additional diabetes-specific barrier to adding regular exercise to their lifestyle. Physiologic mechanisms linked to exercise impairment in diabetes include insulin resistance, cardiac abnormalities, mitochondrial function, and the ability of the body to supply oxygen. In this paper, we highlight the abnormalities of exercise in type 2 diabetes as well as potential therapeutic approaches.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Front Endocrinol (Lausanne) Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Front Endocrinol (Lausanne) Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza