The mitochondrial effects of embelin are independent of its MAP kinase regulation: Role of p53 in conferring selectivity towards cancer cells.

Avisetti, Deepa R; Amireddy, Niharika; Kalivendi, Shasi V

Avisetti, Deepa R; Amireddy, Niharika; Kalivendi, Shasi V.

Afiliación

Avisetti DR; Biochemistry Laboratory, Department of Applied Biology and Academy of Scientific and Innovative Research (AcSIR), CSIR-Indian Institute of Chemical Technology, , Uppal Road, Hyderabad 500007, T.S., India.
Amireddy N; Biochemistry Laboratory, Department of Applied Biology and Academy of Scientific and Innovative Research (AcSIR), CSIR-Indian Institute of Chemical Technology, , Uppal Road, Hyderabad 500007, T.S., India.
Kalivendi SV; Biochemistry Laboratory, Department of Applied Biology and Academy of Scientific and Innovative Research (AcSIR), CSIR-Indian Institute of Chemical Technology, , Uppal Road, Hyderabad 500007, T.S., India. Electronic address: kalivendi@iict.res.in.

Mitochondrion ; 46: 158-163, 2019 05.

Article en En | MEDLINE | ID: mdl-29715507

Asunto(s)

Antineoplásicos/metabolismo; Benzoquinonas/metabolismo; Células Epiteliales/efectos de los fármacos; Neoplasias/patología; Proteína p53 Supresora de Tumor/metabolismo; Células A549; Apoptosis; Humanos; Proteínas Quinasas p38 Activadas por Mitógenos/metabolismo

Palabras clave

Apoptosis; Embelin; Mitochondrial respiration; Oxidative stress; p38 MAP kinase; p53

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Benzoquinonas / Proteína p53 Supresora de Tumor / Células Epiteliales / Neoplasias / Antineoplásicos Límite: Humans Idioma: En Revista: Mitochondrion Año: 2019 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos

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