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Gender differences in outcomes after aortic aneurysm surgery should foster further research to improve screening and prevention programmes.
Nicolini, Francesco; Vezzani, Antonella; Corradi, Francesco; Gherli, Riccardo; Benassi, Filippo; Manca, Tullio; Gherli, Tiziano.
Afiliación
  • Nicolini F; 1 Department of Medicine and Surgery, University of Parma, Italy.
  • Vezzani A; 2 General and Specialistic Surgery Department, Azienda Ospedaliero Universitaria di Parma, Italy.
  • Corradi F; 3 Anaesthesia and Intensive Care Unit, E.O. Ospedali Galliera, Italy.
  • Gherli R; 4 Department of Cardiovascular Sciences, San Camillo Forlanini Hospital, Italy.
  • Benassi F; 2 General and Specialistic Surgery Department, Azienda Ospedaliero Universitaria di Parma, Italy.
  • Manca T; 2 General and Specialistic Surgery Department, Azienda Ospedaliero Universitaria di Parma, Italy.
  • Gherli T; 1 Department of Medicine and Surgery, University of Parma, Italy.
Eur J Prev Cardiol ; 25(1_suppl): 32-41, 2018 06.
Article en En | MEDLINE | ID: mdl-29708035
Background Gender-related biases in outcomes after thoracic aortic surgery are an important factor to consider in the prevention of potential complications related to aortic diseases and in the analysis of surgical results. Methods The aim of this study is to provide an up-to-date review of gender-related differences in the epidemiology, specific risk factors, outcome, and screening and prevention programmes in aortic aneurysms. Results Female patients affected by aortic disease still have worse outcomes and higher early and late mortality than men. It is difficult to plan new specific strategies to improve outcomes in women undergoing major aortic surgery, given that the true explanations for their poorer outcomes are as yet not clearly identified. Some authors recommend further investigation of hormonal or molecular explanations for the sex differences in aortic disease. Others stress the need for quality improvement projects to quantify the preoperative risk in high-risk populations using non-invasive tests such as cardiopulmonary exercise testing. Conclusions The treatment of patients classified as high risk could thus be optimised before surgery becomes necessary by means of numerous strategies, such as the administration of high-dose statin therapy, antiplatelet treatment, optimal control of hypertension, lifestyle improvement with smoking cessation, weight loss and careful control of diabetes. Future efforts are needed to understand better the gender differences in the diagnosis, management and outcome of aortic aneurysm disease, and for appropriate and modern management of female patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aneurisma de la Aorta / Complicaciones Posoperatorias / Procedimientos Quirúrgicos Vasculares / Tamizaje Masivo / Prevención Secundaria Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Aspecto: Determinantes_sociais_saude Límite: Female / Humans / Male Idioma: En Revista: Eur J Prev Cardiol Año: 2018 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aneurisma de la Aorta / Complicaciones Posoperatorias / Procedimientos Quirúrgicos Vasculares / Tamizaje Masivo / Prevención Secundaria Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Aspecto: Determinantes_sociais_saude Límite: Female / Humans / Male Idioma: En Revista: Eur J Prev Cardiol Año: 2018 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido