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DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates.
McLaren, David G; Han, Seongah; Murphy, Beth Ann; Wilsie, Larissa; Stout, Steven J; Zhou, Haihong; Roddy, Thomas P; Gorski, Judith N; Metzger, Daniel E; Shin, Myung K; Reilly, Dermot F; Zhou, Heather H; Tadin-Strapps, Marija; Bartz, Steven R; Cumiskey, Anne-Marie; Graham, Thomas H; Shen, Dong-Ming; Akinsanya, Karen O; Previs, Stephen F; Imbriglio, Jason E; Pinto, Shirly.
Afiliación
  • McLaren DG; Pharmacology, Merck & Co., Inc., Kenilworth, NJ 07033, USA. Electronic address: david.mclaren@merck.com.
  • Han S; Division of Cardio Metabolic Disease, Merck & Co., Inc., Kenilworth, NJ 07033, USA. Electronic address: seongah_han@merck.com.
  • Murphy BA; Pharmacology, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Wilsie L; Division of Cardio Metabolic Disease, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Stout SJ; Pharmacology, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Zhou H; Division of Cardio Metabolic Disease, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Roddy TP; Division of Cardio Metabolic Disease, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Gorski JN; Pharmacology, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Metzger DE; Pharmacology, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Shin MK; Genetics and Pharmacogenomics, Merck & Co., Inc., Boston, MA 02115, USA.
  • Reilly DF; Genetics and Pharmacogenomics, Merck & Co., Inc., Boston, MA 02115, USA.
  • Zhou HH; Division of Cardio Metabolic Disease, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Tadin-Strapps M; Genetics and Pharmacogenomics, Merck & Co., Inc., Boston, MA 02115, USA.
  • Bartz SR; Business Development and Licensing, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Cumiskey AM; Pharmacology, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Graham TH; Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Shen DM; Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Akinsanya KO; Business Development and Licensing, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Previs SF; Division of Cardio Metabolic Disease, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Imbriglio JE; Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Pinto S; Division of Cardio Metabolic Disease, Merck & Co., Inc., Kenilworth, NJ 07033, USA. Electronic address: shirly@kallyope.com.
Cell Metab ; 27(6): 1236-1248.e6, 2018 Jun 05.
Article en En | MEDLINE | ID: mdl-29706567
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triglicéridos / Hepatocitos / Dislipidemias / Diacilglicerol O-Acetiltransferasa / Obesidad Límite: Animals / Humans Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triglicéridos / Hepatocitos / Dislipidemias / Diacilglicerol O-Acetiltransferasa / Obesidad Límite: Animals / Humans Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos