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The role of the pathology department in the preanalytical phase of molecular analyses.
Susman, Sergiu; Berindan-Neagoe, Ioana; Petrushev, Bobe; Pirlog, Radu; Florian, Ioan-Stefan; Mihu, Carmen-Mihaela; Berce, Cristian; Craciun, Lucian; Grewal, Ravnit; Tomuleasa, Ciprian.
Afiliación
  • Susman S; Department of Pathology, Imogen Research Center.
  • Berindan-Neagoe I; Department of Morphological Sciences.
  • Petrushev B; Research Center for Functional Genomics and Translational Medicine.
  • Pirlog R; Research Center for Functional Genomics and Translational Medicine.
  • Florian IS; Department of Morphological Sciences.
  • Mihu CM; Department of Neurosurgery, Iuliu Hatieganu University of Medicine and Pharmacy.
  • Berce C; Department of Morphological Sciences.
  • Craciun L; Research Center for Functional Genomics and Translational Medicine.
  • Grewal R; Department of Morphological Sciences.
  • Tomuleasa C; Department of Hematology, Ion Chiricuta Oncology Institute.
Cancer Manag Res ; 10: 745-753, 2018.
Article en En | MEDLINE | ID: mdl-29695931
After introducing the new molecules for the treatment of patients with tumoral pathology, the therapeutical decision will be taken depending on the molecular profile performed upon the harvested tissues. This major modification makes the molecular and morphological analysis an essential part in the clinical management of patients and the pathologist plays an important role in this process. The quality and reproducibility of the results are imperative today and they depend on both the reliability of the molecular techniques and the quality of the tissue we use in the process. Also, the genomics and proteomics techniques, used increasingly often, require high-quality tissues, and pathology laboratories play a very significant role in the management of all phases of this process. In this paper the parameters which must be followed in order to obtain optimal results within the techniques which analyze nucleic acids and proteins were reviewed.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Cancer Manag Res Año: 2018 Tipo del documento: Article Pais de publicación: Nueva Zelanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Cancer Manag Res Año: 2018 Tipo del documento: Article Pais de publicación: Nueva Zelanda