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Two new anthraquinone derivatives and one new triarylbenzophenone analog from Selaginella tamariscina.
Liu, Rui; Zou, Hui; Zou, Zhen-Xing; Cheng, Fei; Yu, Xia; Xu, Ping-Sheng; Li, Xiao-Min; Li, Dai; Xu, Kang-Ping; Tan, Gui-Shan.
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  • Liu R; Xiangya Hospital of Central South University , Changsha, China.
  • Zou H; Xiangya School of Pharmaceutical Sciences, Central South University , Changsha, China.
  • Zou ZX; Xiangya School of Pharmaceutical Sciences, Central South University , Changsha, China.
  • Cheng F; School of Medicine, Hunan Normal University , Changsha, China.
  • Yu X; Xiangya Hospital of Central South University , Changsha, China.
  • Xu PS; Xiangya Hospital of Central South University , Changsha, China.
  • Li XM; Xiangya School of Pharmaceutical Sciences, Central South University , Changsha, China.
  • Li D; Xiangya Hospital of Central South University , Changsha, China.
  • Xu KP; Xiangya Hospital of Central South University , Changsha, China.
  • Tan GS; Xiangya Hospital of Central South University , Changsha, China.
Nat Prod Res ; 34(19): 2709-2714, 2020 Oct.
Article en En | MEDLINE | ID: mdl-29658323
Two new anthraquinone derivatives, selaginones A (1) and B (2), and one new triarylbenzophenone analog, selagibenzophenone B (3), were isolated from Selaginella tamariscina (Beauv.) Spring. Their structures were established by 1D-, 2D-NMR and HR-ESI-MS data. Compounds 1 and 2 represent the uncommon examples of aryl substituted anthraquinone derivatives. Especially, compound 2 is a unique anthranone with exceptional structural feature, in which a p-hydroxyphenyl moiety is attached to the C-10 position. Compound 3 is the second naturally occurring triarylbenzophenone and showed moderate activity against SMCC-7721 and MHCC97-H cell lines with IC50 values of 39.8, 51.5 µM respectively.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antraquinonas / Selaginellaceae Límite: Humans Idioma: En Revista: Nat Prod Res Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antraquinonas / Selaginellaceae Límite: Humans Idioma: En Revista: Nat Prod Res Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido