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Intra-tumour diversification in colorectal cancer at the single-cell level.
Roerink, Sophie F; Sasaki, Nobuo; Lee-Six, Henry; Young, Matthew D; Alexandrov, Ludmil B; Behjati, Sam; Mitchell, Thomas J; Grossmann, Sebastian; Lightfoot, Howard; Egan, David A; Pronk, Apollo; Smakman, Niels; van Gorp, Joost; Anderson, Elizabeth; Gamble, Stephen J; Alder, Chris; van de Wetering, Marc; Campbell, Peter J; Stratton, Michael R; Clevers, Hans.
Afiliación
  • Roerink SF; Cancer Ageing and Somatic Mutations Programme, Wellcome Trust Sanger Insitute, Hinxton, UK.
  • Sasaki N; Hubrecht Institute, University Medical Center Utrecht and Princess Maxima Center, Utrecht, The Netherlands.
  • Lee-Six H; Department of Gastroenterology, Keio University School of Medicine, Tokyo, Japan.
  • Young MD; Cancer Ageing and Somatic Mutations Programme, Wellcome Trust Sanger Insitute, Hinxton, UK.
  • Alexandrov LB; Cancer Ageing and Somatic Mutations Programme, Wellcome Trust Sanger Insitute, Hinxton, UK.
  • Behjati S; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Mitchell TJ; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
  • Grossmann S; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
  • Lightfoot H; Cancer Ageing and Somatic Mutations Programme, Wellcome Trust Sanger Insitute, Hinxton, UK.
  • Egan DA; Department of Paediatrics, University of Cambridge, Cambridge, UK.
  • Pronk A; Cancer Ageing and Somatic Mutations Programme, Wellcome Trust Sanger Insitute, Hinxton, UK.
  • Smakman N; Academic Urology Group, Department of Surgery, Addenbrooke's Hospitals NHS Foundation Trust, University of Cambridge, Cambridge, UK.
  • van Gorp J; Cancer Ageing and Somatic Mutations Programme, Wellcome Trust Sanger Insitute, Hinxton, UK.
  • Anderson E; Cancer Ageing and Somatic Mutations Programme, Wellcome Trust Sanger Insitute, Hinxton, UK.
  • Gamble SJ; Cell Screening Core, Department of Cell Biology, Center for Molecular Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands.
  • Alder C; Core Life Analytics, Utrecht, The Netherlands.
  • van de Wetering M; Department of Surgery, Diakonessenhuis, Utrecht, The Netherlands.
  • Campbell PJ; Department of Surgery, Diakonessenhuis, Utrecht, The Netherlands.
  • Stratton MR; Department of Pathology, Diakonessenhuis, Utrecht, The Netherlands.
  • Clevers H; Cancer Ageing and Somatic Mutations Programme, Wellcome Trust Sanger Insitute, Hinxton, UK.
Nature ; 556(7702): 457-462, 2018 04.
Article en En | MEDLINE | ID: mdl-29643510

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Células Clonales / Evolución Molecular / Análisis de la Célula Individual / Mutación / Antineoplásicos Límite: Humans Idioma: En Revista: Nature Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Células Clonales / Evolución Molecular / Análisis de la Célula Individual / Mutación / Antineoplásicos Límite: Humans Idioma: En Revista: Nature Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido