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Generation of tumor antigen-specific murine CD8+ T cells with enhanced anti-tumor activity via highly efficient CRISPR/Cas9 genome editing.
Ouchi, Yasuo; Patil, Ashwini; Tamura, Yusuke; Nishimasu, Hiroshi; Negishi, Aina; Paul, Sudip Kumar; Takemura, Naoki; Satoh, Takeshi; Kimura, Yasumasa; Kurachi, Makoto; Nureki, Osamu; Nakai, Kenta; Kiyono, Hiroshi; Uematsu, Satoshi.
Afiliación
  • Ouchi Y; Department of Mucosal Immunology, School of Medicine, Chiba University, Inohana, Chuo-ku, Chiba, Japan.
  • Patil A; Human Genome Center, The Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
  • Tamura Y; Division of Innate Immune Regulation, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
  • Nishimasu H; Department of Biological Sciences, Graduate School of Science, University of Tokyo; JST, PRESTO, Yayoi, Bunkyo, Tokyo, Japan.
  • Negishi A; Department of Mucosal Immunology, School of Medicine, Chiba University, Inohana, Chuo-ku, Chiba, Japan.
  • Paul SK; Department of Mucosal Immunology, School of Medicine, Chiba University, Inohana, Chuo-ku, Chiba, Japan.
  • Takemura N; Department of Mucosal Immunology, School of Medicine, Chiba University, Inohana, Chuo-ku, Chiba, Japan.
  • Satoh T; Division of Innate Immune Regulation, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
  • Kimura Y; Division of Systems Immunology, The Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
  • Kurachi M; Division of Systems Immunology, The Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
  • Nureki O; Department of Microbiology and Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Nakai K; Department of Biological Sciences, Graduate School of Science, University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, Japan.
  • Kiyono H; Human Genome Center, The Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
  • Uematsu S; International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
Int Immunol ; 30(4): 141-154, 2018 04 03.
Article en En | MEDLINE | ID: mdl-29617862
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Especificidad del Receptor de Antígeno de Linfocitos T / Sistemas CRISPR-Cas / Edición Génica / Antígenos de Neoplasias / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Int Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Especificidad del Receptor de Antígeno de Linfocitos T / Sistemas CRISPR-Cas / Edición Génica / Antígenos de Neoplasias / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Int Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido