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Discovery of a highly selective JAK3 inhibitor for the treatment of rheumatoid arthritis.
Pei, Heying; He, Linhong; Shao, Mingfeng; Yang, Zhuang; Ran, Yan; Li, Dan; Zhou, Yuanyuan; Tang, Minghai; Wang, Taijin; Gong, Yanqiu; Chen, Xiaoxin; Yang, Shengyong; Xiang, Mingli; Chen, Lijuan.
Afiliación
  • Pei H; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
  • He L; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
  • Shao M; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
  • Yang Z; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
  • Ran Y; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
  • Li D; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
  • Zhou Y; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
  • Tang M; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
  • Wang T; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
  • Gong Y; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
  • Chen X; Guangdong Zhongsheng Pharmaceutical Co., Ltd., Dongguan, Guangdong, 523325, China.
  • Yang S; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
  • Xiang M; State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China. xiang_mingli@scu.edu.cn.
  • Chen L; Guangdong Zhongsheng Pharmaceutical Co., Ltd., Dongguan, Guangdong, 523325, China. xiang_mingli@scu.edu.cn.
Sci Rep ; 8(1): 5273, 2018 03 27.
Article en En | MEDLINE | ID: mdl-29588471
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperidinas / Artritis Reumatoide / Inhibidores de Proteínas Quinasas / Janus Quinasa 3 / Articulaciones Límite: Animals / Female / Humans / Male Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperidinas / Artritis Reumatoide / Inhibidores de Proteínas Quinasas / Janus Quinasa 3 / Articulaciones Límite: Animals / Female / Humans / Male Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido