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Methotrexate upregulates circadian transcriptional factors PAR bZIP to induce apoptosis on rheumatoid arthritis synovial fibroblasts.
Suzuki, Kohjin; Yoshida, Kohsuke; Ueha, Takeshi; Kaneshiro, Kenta; Nakai, Ayako; Hashimoto, Naonori; Uchida, Koto; Hashimoto, Teppei; Kawasaki, Yoshiko; Shibanuma, Nao; Nakagawa, Natsuko; Sakai, Yoshitada; Hashiramoto, Akira.
Afiliación
  • Suzuki K; Department of Biophysics, Kobe University Graduate School of Health Sciences, Tomogaoka 7-10-2, Suma-ku, Kobe, 654-0142, Japan.
  • Yoshida K; Department of Biophysics, Kobe University Graduate School of Health Sciences, Tomogaoka 7-10-2, Suma-ku, Kobe, 654-0142, Japan.
  • Ueha T; Division of Rehabilitation Medicine, Kobe University Graduate School of Medicine, Kobe, 650-0017, Japan.
  • Kaneshiro K; Department of Biophysics, Kobe University Graduate School of Health Sciences, Tomogaoka 7-10-2, Suma-ku, Kobe, 654-0142, Japan.
  • Nakai A; Department of Biophysics, Kobe University Graduate School of Health Sciences, Tomogaoka 7-10-2, Suma-ku, Kobe, 654-0142, Japan.
  • Hashimoto N; Department of Biophysics, Kobe University Graduate School of Health Sciences, Tomogaoka 7-10-2, Suma-ku, Kobe, 654-0142, Japan.
  • Uchida K; Department of Biophysics, Kobe University Graduate School of Health Sciences, Tomogaoka 7-10-2, Suma-ku, Kobe, 654-0142, Japan.
  • Hashimoto T; Department of Rheumatology, Kobe Kaisei Hospital, Kobe, 657-0068, Japan.
  • Kawasaki Y; Department of Rheumatology, Kobe Kaisei Hospital, Kobe, 657-0068, Japan.
  • Shibanuma N; Department of Orthopedic Surgery, Kobe Kaisei Hospital, Kobe, 657-0068, Japan.
  • Nakagawa N; Department of Rheumatology, Hyogo Prefectural Kakogawa Medical Center, Kakogawa, 675-0003, Japan.
  • Sakai Y; Division of Rehabilitation Medicine, Kobe University Graduate School of Medicine, Kobe, 650-0017, Japan.
  • Hashiramoto A; Department of Biophysics, Kobe University Graduate School of Health Sciences, Tomogaoka 7-10-2, Suma-ku, Kobe, 654-0142, Japan. hash@med.kobe-u.ac.jp.
Arthritis Res Ther ; 20(1): 55, 2018 03 22.
Article en En | MEDLINE | ID: mdl-29566767
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Reumatoide / Membrana Sinovial / Factores de Transcripción / Proteínas Nucleares / Metotrexato / Proteínas de Unión al ARN / Colágeno Tipo XI / Relojes Circadianos Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Arthritis Res Ther Asunto de la revista: REUMATOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Reumatoide / Membrana Sinovial / Factores de Transcripción / Proteínas Nucleares / Metotrexato / Proteínas de Unión al ARN / Colágeno Tipo XI / Relojes Circadianos Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Arthritis Res Ther Asunto de la revista: REUMATOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido