Lyotropic Liquid Crystalline Nanoparticles of Amphotericin B: Implication of Phytantriol and Glyceryl Monooleate on Bioavailability Enhancement.

Jain, Sanyog; Yadav, Pooja; Swami, Rajan; Swarnakar, Nitin Kumar; Kushwah, Varun; Katiyar, Sameer S

Jain, Sanyog; Yadav, Pooja; Swami, Rajan; Swarnakar, Nitin Kumar; Kushwah, Varun; Katiyar, Sameer S.

Afiliación

Jain S; Centre for Pharmaceutical Nanotechnology, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Mohali, Punjab, 160062, India. sanyogjain@niper.ac.in.
Yadav P; Centre for Pharmaceutical Nanotechnology, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Mohali, Punjab, 160062, India.
Swami R; Centre for Pharmaceutical Nanotechnology, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Mohali, Punjab, 160062, India.
Swarnakar NK; Centre for Pharmaceutical Nanotechnology, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Mohali, Punjab, 160062, India.
Kushwah V; Centre for Pharmaceutical Nanotechnology, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Mohali, Punjab, 160062, India.
Katiyar SS; Centre for Pharmaceutical Nanotechnology, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Mohali, Punjab, 160062, India.

AAPS PharmSciTech ; 19(4): 1699-1711, 2018 May.

Article en En | MEDLINE | ID: mdl-29532426

Asunto(s)

Anfotericina B/farmacocinética; Alcoholes Grasos/farmacocinética; Glicéridos/farmacocinética; Cristales Líquidos; Nanopartículas/metabolismo; Anfotericina B/química; Animales; Disponibilidad Biológica; Células CACO-2; Preparaciones de Acción Retardada/química; Preparaciones de Acción Retardada/farmacocinética; Alcoholes Grasos/química; Femenino; Glicéridos/química; Humanos; Cristales Líquidos/química; Ratones; Nanopartículas/química; Tamaño de la Partícula; Ratas; Ratas Sprague-Dawley

Palabras clave

amphotericin B; bioavailability; hemotoxicity; lipids; nephrotoxicity; oral delivery

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Anfotericina B / Cristales Líquidos / Nanopartículas / Alcoholes Grasos / Glicéridos Límite: Animals / Female / Humans Idioma: En Revista: AAPS PharmSciTech Asunto de la revista: FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

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