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Nonadministration of medication doses for venous thromboembolism prophylaxis in a cohort of hospitalized patients.
Popoola, Victor O; Lau, Brandyn D; Tan, Esther; Shaffer, Dauryne L; Kraus, Peggy S; Farrow, Norma E; Hobson, Deborah B; Aboagye, Jonathan K; Streiff, Michael B; Haut, Elliott R.
Afiliación
  • Popoola VO; Division of Acute Care Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, MD.
  • Lau BD; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD.
  • Tan E; Division of Health Sciences Informatics, Johns Hopkins School of Medicine, Baltimore, MD.
  • Shaffer DL; Division of Acute Care Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, MD.
  • Kraus PS; Department of Nursing, Johns Hopkins Hospital, Baltimore, MD.
  • Farrow NE; Department of Pharmacy, Johns Hopkins Hospital, Baltimore, MD.
  • Hobson DB; Division of Acute Care Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, MD.
  • Aboagye JK; Department of Nursing, Johns Hopkins Hospital, Baltimore, MD.
  • Streiff MB; Division of Acute Care Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, MD.
  • Haut ER; Armstrong Institute for Patient Safety and Quality, Johns Hopkins Medicine, Baltimore, MD.
Am J Health Syst Pharm ; 75(6): 392-397, 2018 Mar 15.
Article en En | MEDLINE | ID: mdl-29523536
PURPOSE: Results of a study to characterize patterns of nonadministration of medication doses for venous thromboembolism (VTE) prevention among hospitalized patients are presented. METHODS: The electronic records of all patients admitted to 4 floors of a medical center during a 1-month period were examined to identify patients whose records indicated at least 1 nonadministered dose of medication for VTE prophylaxis. Proportions of nonadministered doses by medication type, intended route of administration, and VTE risk categorization were compared; reasons for nonadministration were evaluated. RESULTS: Overall, 12.7% of all medication doses prescribed to patients in the study cohort (n = 75) during the study period (857 of 6,758 doses in total) were not administered. Nonadministration of 1 or more doses of VTE prophylaxis medication was nearly twice as likely for subcutaneous anticoagulants than for all other medication types (231 of 1,112 doses [20.8%] versus 626 of 5,646 doses [11.2%], p < 0.001). For all medications prescribed, the most common reason for nonadministration was patient refusal (559 of 857 doses [65.2%]); the refusal rate was higher for subcutaneous anticoagulants than for all other medication categories (82.7% versus 58.8%, p < 0.001). Doses of antiretrovirals, immunosuppressives, antihypertensives, psychiatric medications, analgesics, and antiepileptics were less commonly missed than doses of electrolytes, vitamins, and gastrointestinal medications. CONCLUSION: Scheduled doses of subcutaneous anticoagulants for hospitalized patients were more likely to be missed than doses of all other medication types.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Negativa del Paciente al Tratamiento / Tromboembolia Venosa / Cumplimiento de la Medicación / Anticoagulantes Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Am J Health Syst Pharm Asunto de la revista: FARMACIA / HOSPITAIS Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Negativa del Paciente al Tratamiento / Tromboembolia Venosa / Cumplimiento de la Medicación / Anticoagulantes Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Am J Health Syst Pharm Asunto de la revista: FARMACIA / HOSPITAIS Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido