Apoptosis/genética; Isquemia Encefálica/genética; Regulación de la Expresión Génica/genética; Inflamación/genética; Janus Quinasa 2/biosíntesis; Janus Quinasa 2/genética; MicroARNs/genética; Factor de Transcripción STAT3/genética; Transducción de Señal/genética; Regiones no Traducidas 3'/genética; Animales; Infarto Encefálico/patología; Masculino; Ratones; Enfermedades del Sistema Nervioso/etiología; Enfermedades del Sistema Nervioso/genética; Cultivo Primario de Células; Accidente Cerebrovascular/genética; Regulación hacia Arriba

3ʹUTR = 3ʹ untranslated region; CCA = common carotid artery; DMEM = Dulbecco's modified Eagle's medium; ELISA = enzyme-linked immunosorbent assay; FBS = fetal bovine serum; GAPDH = glyceraldehyde 3-phosphate dehydrogenase; ICA = internal carotid artery; IL-1 = interleukin-1; JAK = Janus tyrosine kinase; JAK2/STAT3; LDH = lactate dehydrogenase; MCAO; MCAO = middle cerebral artery occlusion; MMP-9 = matrix metalloproteinase­9; MTT = 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; OGD = oxygen-glucose deprivation; OGD/R = oxygen-glucose deprivation/reoxygenation; OGD2/R24 = 2 hours of OGD and 24 hours of reoxygenation; PCN = primary cortical neuronal; SDS-PAGE = sodium dodecyl sulfate­polyacrylamide gel electrophoresis; STAT = signal transducer and activator of transcription; TNF-α = tumor necrosis factor­α; TTC = 2,3,5-triphenyltetrazolium chloride; TUNEL = terminal deoxynucleotidyl transferase­mediated deoxyuridine triphosphate nick-end labeling; iNOS = inducible nitric oxide synthase; ischemic injury; miR-216a; miR-NC = miRNA negative control; miRNA = microRNA; qRT-PCR = quantitative reverse-transcriptase polymerase chain reaction; siJAK2 = JAK2 short-interfering RNA