Human Ska complex and Ndc80 complex interact to form a load-bearing assembly that strengthens kinetochore-microtubule attachments.

Helgeson, Luke A; Zelter, Alex; Riffle, Michael; MacCoss, Michael J; Asbury, Charles L; Davis, Trisha N

Helgeson, Luke A; Zelter, Alex; Riffle, Michael; MacCoss, Michael J; Asbury, Charles L; Davis, Trisha N.

Afiliación

Helgeson LA; Department of Biochemistry, University of Washington, Seattle, WA 98195.
Zelter A; Department of Biochemistry, University of Washington, Seattle, WA 98195.
Riffle M; Department of Biochemistry, University of Washington, Seattle, WA 98195.
MacCoss MJ; Department of Genome Sciences, University of Washington, Seattle, WA 98195.
Asbury CL; Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195.
Davis TN; Department of Biochemistry, University of Washington, Seattle, WA 98195; tdavis@uw.edu.

Proc Natl Acad Sci U S A ; 115(11): 2740-2745, 2018 03 13.

Article en En | MEDLINE | ID: mdl-29487209

Asunto(s)

Cinetocoros/metabolismo; Microtúbulos/metabolismo; Proteínas Nucleares/metabolismo; Proteínas de Ciclo Celular; Segregación Cromosómica; Proteínas del Citoesqueleto; Humanos; Cinetocoros/química; Proteínas Asociadas a Microtúbulos/genética; Proteínas Asociadas a Microtúbulos/metabolismo; Microtúbulos/química; Microtúbulos/genética; Proteínas Nucleares/genética; Unión Proteica

Palabras clave

Ndc80 complex; Ska complex; kinetochore; microtubules; optical tweezers

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Cinetocoros / Microtúbulos Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos

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