Your browser doesn't support javascript.
loading
"The devil's in the detail": Release of an expanded, enhanced and dynamically revised forensic STR Sequence Guide.
Phillips, C; Gettings, K Butler; King, J L; Ballard, D; Bodner, M; Borsuk, L; Parson, W.
Afiliación
  • Phillips C; Forensic Genetics Unit, Institute of Forensic Sciences, University of Santiago de Compostela, Spain. Electronic address: c.phillips@mac.com.
  • Gettings KB; National Institute of Standards and Technology, Biomolecular Measurement Division, Gaithersburg, MD, USA.
  • King JL; Institute of Applied Genetics, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, Fort Worth, TX, USA.
  • Ballard D; King's Forensics, King's College London, Franklin-Wilkins Building, London, UK.
  • Bodner M; Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria.
  • Borsuk L; National Institute of Standards and Technology, Biomolecular Measurement Division, Gaithersburg, MD, USA.
  • Parson W; Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria; Forensic Science Program, The Pennsylvania State University, University Park, PA, USA, USA.
Forensic Sci Int Genet ; 34: 162-169, 2018 05.
Article en En | MEDLINE | ID: mdl-29486434
The STR sequence template file published in 2016 as part of the considerations from the DNA Commission of the International Society for Forensic Genetics on minimal STR sequence nomenclature requirements, has been comprehensively revised and audited using the latest GRCh38 genome assembly. The list of forensic STRs characterized was expanded by including supplementary autosomal, X- and Y-chromosome microsatellites in less common use for routine DNA profiling, but some likely to be adopted in future massively parallel sequencing (MPS) STR panels. We outline several aspects of sequence alignment and annotation that required care and attention to detail when comparing sequences to GRCh37 and GRCh38 assemblies, as well as the necessary matching of MPS-based allele descriptions to previously established repeat region structures described in initial sequencing studies of the less well known forensic STRs. The revised sequence guide is now available in a dynamically updated FTP format from the STRidER website with a date-stamped change log to allow users to explore their own MPS data with the most up-to-date forensic STR sequence information compiled in a simple guide.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Programas Informáticos / Dermatoglifia del ADN / Repeticiones de Microsatélite Límite: Humans Idioma: En Revista: Forensic Sci Int Genet Asunto de la revista: GENETICA / JURISPRUDENCIA Año: 2018 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Programas Informáticos / Dermatoglifia del ADN / Repeticiones de Microsatélite Límite: Humans Idioma: En Revista: Forensic Sci Int Genet Asunto de la revista: GENETICA / JURISPRUDENCIA Año: 2018 Tipo del documento: Article Pais de publicación: Países Bajos