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European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009-2014.
Dittmar, Daan; Uter, Wolfgang; Bauer, Andrea; Fortina, Ana B; Bircher, Andreas J; Czarnecka-Operacz, Magdalena; Dugonik, Aleksandra; Elsner, Peter; Gallo, Rosella; Ghaffar, Sharizan A; Giménez-Arnau, Anna; Johnston, Graham A; Krecisz, Beata; Filon, Francesca L; Rustemeyer, Thomas; Sadowska-Przytocka, Anna; Sánchez-Pérez, Javier; Schnuch, Axel; Simon, Dagmar; Spiewak, Radoslaw; Spring, Philipp; Corradin, Maria T; Valiukeviciene, Skaidra; Vok, Marko; Weisshaar, Elke; Wilkinson, Mark; Schuttelaar, Marie L.
Afiliación
  • Dittmar D; University of Groningen, University Medical Centre Groningen, Department of Dermatology, 9700 RB Groningen, The Netherlands.
  • Uter W; Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen/Nürnberg, 91054 Erlangen, Germany.
  • Bauer A; Department of Dermatology, University Allergy Centre, University Hospital Carl Gustav Carus, Technical University of Dresden, 01307 Dresden, Germany.
  • Fortina AB; Dermatology Unit, Department of Paediatrics, University of Padova, 35137 Padova, Italy.
  • Bircher AJ; Allergy Unit, Department of Dermatology, University Hospital, 4031 Basel, Switzerland.
  • Czarnecka-Operacz M; Dermatology Department, University of Medical Sciences, 60-355 Poznan, Poland.
  • Dugonik A; Department of Dermatology, University Medical Centre Maribor, 2000 Maribor, Slovenia.
  • Elsner P; Department of Dermatology, University Hospital Jena, 07743 Jena, Germany.
  • Gallo R; Section of Dermatology, DISSAL - Department of Health Sciences, University of Genoa, 16132 Genoa, Italy.
  • Ghaffar SA; Department of Dermatology, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
  • Giménez-Arnau A; Department of Dermatology, Hospital del Mar. Universitat Autònoma and Pompeu Fabra, 08003 Barcelona, Spain.
  • Johnston GA; Department of Dermatology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK.
  • Krecisz B; Faculty of Medicine and Health Science, The Jan Kochanowski University, 25-317 Kielce, Poland.
  • Filon FL; Unit of Occupational Medicine, University of Trieste, 34129 Trieste, Italy.
  • Rustemeyer T; Department of Dermatology, Free University of Amsterdam, 1081 HV Amsterdam, The Netherlands.
  • Sadowska-Przytocka A; Dermatology Department, University of Medical Sciences, 60-355 Poznan, Poland.
  • Sánchez-Pérez J; Dermatology Department, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria la Princesa (IIS-IP), 28006 Madrid, Spain.
  • Schnuch A; Information Network of Departments of Dermatology at the University of Göttingen, 37075 Göttingen, Germany.
  • Simon D; Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
  • Spiewak R; Department of Experimental Dermatology and Cosmetology, Jagiellonian University Medical College, 30-688 Krakow, Poland.
  • Spring P; Department of Dermatology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.
  • Corradin MT; Department of Dermatology, Hospital of Pordenone, 33170 Pordenone, Italy.
  • Valiukeviciene S; Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences, 44307 Kaunas, Lithuania.
  • Vok M; Lithuanian University of Health Sciences Hospital, 50009 Kaunas, Lithuania.
  • Weisshaar E; Dermatoveneroloska ambulanta, 6310 Izola, Slovenia.
  • Wilkinson M; Department of Clinical Social Medicine, Occupational and Environmental Dermatology, University Hospital Heidelberg, 69117 Germany.
  • Schuttelaar ML; Dermatology, Leeds Teaching Hospitals NHS Trust, Leeds LS7 4SA, UK.
Contact Dermatitis ; 78(6): 373-385, 2018 Jun.
Article en En | MEDLINE | ID: mdl-29468728
BACKGROUND: Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered to reflect increased susceptibility to developing a contact allergy, and is likely to be associated with an impaired quality of life. OBJECTIVES: To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization. METHODS: Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed. RESULTS: A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02%, ranging from 12.7% (Austria) to 4.6% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization. CONCLUSIONS: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas del Parche / Alérgenos / Vigilancia de la Población Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Aspecto: Patient_preference Límite: Adult / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Contact Dermatitis Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas del Parche / Alérgenos / Vigilancia de la Población Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Aspecto: Patient_preference Límite: Adult / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Contact Dermatitis Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido