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Detection of endocarditis bacteria in tonsillar mucosa of Afghan population.
Ruggiero, F; Carbone, D; Mugavero, R; Palmieri, A; Lauritano, D; Baggi, L; Nardone, M; Carinci, F; Martinelli, M.
Afiliación
  • Ruggiero F; Military Policlinic of Rome, Medical Department, Cardiological Unit, Rome, Italy.
  • Carbone D; Military Policlinic of Rome, Department of Urgency and Surgery, Operative Unit of Odontostomatology, Rome, Italy.
  • Mugavero R; Department of Electronic Engineering, University of Tor Vergata, Rome, Italy.
  • Palmieri A; OSDIFE, University of Tor Vergata, Rome, Italy
  • Lauritano D; CUFS, University of San Marino.
  • Baggi L; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy
  • Nardone M; Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy
  • Carinci F; Department of Clinical Sciences and Translational Medicine, University of Tor Vergata, Rome, Italy
  • Martinelli M; Ministry of Public Health, Rome, Italy
J Biol Regul Homeost Agents ; 32(2 Suppl. 1): 179-183, 2018.
Article en En | MEDLINE | ID: mdl-29460538
Endocarditis is a cardiovascular disease caused by the inflammation of the inner tissues of the heart, the endocardium, usually of the valves. Bacteraemia is essential in the development of endocarditis, and there are some findings that the main pathogens of endocarditis are viridans group streptococci: Streptococcus oralis, Streptococcus sanguinis, and Enterococcus faecalis. There is strong evidence that endocarditis bacteria are present in the tonsillar microbiota, so that tonsillar infection is associated with an increased risk of endocarditis. The aim of this manuscript is to investigate the presence of the main pathogens of endocarditis in tonsillar microbiota of an Afghan population group. A sample of 80 tonsil swabs were analyzed by quantitative real time PCR to detect endocarditis pathogens and an estimation of the total bacterial load. The median bacterial load in PCR reaction was 1.4x106 (interquartile range 4,7x105 - 2,9x106). Three species, S. Oralis, S. Sanguinis, and E. Faecalis were found in large amounts in all specimens. On the other hand, S. Mitis was never detected. The S. Aureus was found in 3 samples with a prevalence of 0.04 (C.I. 0.01-0.10). The S. Mutans was found in 33 samples with a prevalence of 0.41 (C.I. 0.31-0.52). Endocarditis bacteria has been found into the tonsillar microbiota, so there is sufficient evidence to justify that the oral cavity is a reservoir of endocarditis bacteria that can have a significant impact on the cardiovascular function.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacterias / Tonsila Palatina / Endocarditis / Membrana Mucosa Tipo de estudio: Diagnostic_studies / Risk_factors_studies Límite: Humans País/Región como asunto: Asia Idioma: En Revista: J Biol Regul Homeost Agents Asunto de la revista: BIOLOGIA / BIOQUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia
Buscar en Google
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Imprimir
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacterias / Tonsila Palatina / Endocarditis / Membrana Mucosa Tipo de estudio: Diagnostic_studies / Risk_factors_studies Límite: Humans País/Región como asunto: Asia Idioma: En Revista: J Biol Regul Homeost Agents Asunto de la revista: BIOLOGIA / BIOQUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia