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Tea Polyphenols and Prevention of Epigenetic Aberrations in Cancer.
Bag, Arundhati; Bag, Niladri.
Afiliación
  • Bag A; Department of Medical Biotechnology, Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok, Sikkim, India.
  • Bag N; Department of Horticulture, Sikkim University, Gangtok, Sikkim, India.
J Nat Sci Biol Med ; 9(1): 2-5, 2018.
Article en En | MEDLINE | ID: mdl-29456384
Tea polyphenols are secondary metabolites of tea plants and are well known for beneficial health effects. They can protect from a variety of illnesses including cancers. Tea polyphenols can prevent cancer by modulating epigenetic aberrations taking place in DNA methylation, histone modifications, and micro-RNAs. By altering these epimutations, they regulate chromatin dynamics and expression of genes those induce or suppress cancer formation. However, majority of the studies in existing literature are carried out for green tea polyphenols rather than black tea polyphenols despite the fact that black tea is the most commonly consumed form of tea (78%) followed by green tea (20%) and other forms of tea. Research findings indicate that tea polyphenols may be potential source from which drugs with less side effects and affordable price can be developed.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Nat Sci Biol Med Año: 2018 Tipo del documento: Article País de afiliación: India Pais de publicación: India

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Nat Sci Biol Med Año: 2018 Tipo del documento: Article País de afiliación: India Pais de publicación: India