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Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway.
Li, Mingyue; Yue, Grace Gar-Lee; Song, Li-Hua; Huang, Mao-Bo; Lee, Julia Kin-Ming; Tsui, Stephen Kwok-Wing; Fung, Kwok-Pui; Tan, Ning-Hua; Lau, Clara Bik-San.
Afiliación
  • Li M; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
  • Yue GG; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong; State Key Laboratory of Phytochemistry and Plant Resources in West China, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
  • Song LH; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
  • Huang MB; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
  • Lee JK; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong; State Key Laboratory of Phytochemistry and Plant Resources in West China, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
  • Tsui SK; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
  • Fung KP; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong; State Key Laboratory of Phytochemistry and Plant Resources in West China, The Chinese Univer
  • Tan NH; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. Electronic address: nhtan@cpu.edu.cn.
  • Lau CB; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong; State Key Laboratory of Phytochemistry and Plant Resources in West China, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong. Electronic address: claralau@cuhk.edu.hk.
Biochem Pharmacol ; 150: 191-201, 2018 04.
Article en En | MEDLINE | ID: mdl-29454618
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sesquiterpenos / Neoplasias Colorrectales / Transducción de Señal / Interleucina-6 / Factor de Transcripción STAT3 / Inhibidores de Crecimiento / Lactonas Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Biochem Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: Hong Kong Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sesquiterpenos / Neoplasias Colorrectales / Transducción de Señal / Interleucina-6 / Factor de Transcripción STAT3 / Inhibidores de Crecimiento / Lactonas Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Biochem Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: Hong Kong Pais de publicación: Reino Unido