Apocynum venetum leaf extract reverses depressive-like behaviors in chronically stressed rats by inhibiting oxidative stress and apoptosis.

Li, Xiangting; Wu, Ting; Yu, Zhonghai; Li, Tingting; Zhang, Jingsi; Zhang, Zhennian; Cai, Min; Zhang, Wen; Xiang, Jun; Cai, Dingfang

Li, Xiangting; Wu, Ting; Yu, Zhonghai; Li, Tingting; Zhang, Jingsi; Zhang, Zhennian; Cai, Min; Zhang, Wen; Xiang, Jun; Cai, Dingfang.

Afiliación

Li X; Department of Integrative Medicine, Zhongshan Hospital, Fudan University, China; Institute of Neurology, Academy of Integrative Medicine, Fudan University, Shanghai 200032, China.
Wu T; Department of Integrative Medicine, Zhongshan Hospital, Fudan University, China; Institute of Neurology, Academy of Integrative Medicine, Fudan University, Shanghai 200032, China.
Yu Z; Department of Integrative Medicine, Zhongshan Hospital, Fudan University, China; Institute of Neurology, Academy of Integrative Medicine, Fudan University, Shanghai 200032, China.
Li T; Department of Neurology, Shuguang Hospital, Shanghai University Traditional Chinese Medicine, Shanghai 201203, China.
Zhang J; Department of Integrative Medicine, Zhongshan Hospital, Fudan University, China; Institute of Neurology, Academy of Integrative Medicine, Fudan University, Shanghai 200032, China.
Zhang Z; Department of Integrative Medicine, Zhongshan Hospital, Fudan University, China; Institute of Neurology, Academy of Integrative Medicine, Fudan University, Shanghai 200032, China.
Cai M; Department of Integrative Medicine, Zhongshan Hospital, Fudan University, China; Institute of Neurology, Academy of Integrative Medicine, Fudan University, Shanghai 200032, China.
Zhang W; Department of Integrative Medicine, Zhongshan Hospital, Fudan University, China; Institute of Neurology, Academy of Integrative Medicine, Fudan University, Shanghai 200032, China.
Xiang J; Department of Integrative Medicine, Zhongshan Hospital, Fudan University, China; Institute of Neurology, Academy of Integrative Medicine, Fudan University, Shanghai 200032, China. Electronic address: xiang.jun@mail.zs-hospital.sh.cn.
Cai D; Department of Integrative Medicine, Zhongshan Hospital, Fudan University, China; Institute of Neurology, Academy of Integrative Medicine, Fudan University, Shanghai 200032, China. Electronic address: dingfangcai@163.com.

Biomed Pharmacother ; 100: 394-406, 2018 Apr.

Article en En | MEDLINE | ID: mdl-29454288

Asunto(s)

Apocynum; Apoptosis/efectos de los fármacos; Depresión/metabolismo; Estrés Oxidativo/efectos de los fármacos; Extractos Vegetales/farmacología; Estrés Psicológico/metabolismo; Animales; Antidepresivos/aislamiento & purificación; Antidepresivos/farmacología; Antidepresivos/uso terapéutico; Apoptosis/fisiología; Enfermedad Crónica; Depresión/tratamiento farmacológico; Relación Dosis-Respuesta a Droga; Masculino; Estrés Oxidativo/fisiología; Extractos Vegetales/aislamiento & purificación; Extractos Vegetales/uso terapéutico; Hojas de la Planta; Ratas; Ratas Wistar; Estrés Psicológico/tratamiento farmacológico

Palabras clave

Apocynum venetum leaf extract; Apoptosis; Chronic unpredictable mild stress; Cytochrome c (CID: 439171); Fluoxetine hydrochloride (CID: 62857); Hydrogen peroxide (CID: 784); Hyperoside (CID: 5281643); Isoquercitrin (CID: 5280804); Major depressive disorder; Malondialdehyde (CID: 10964); Oxidative stress; Quercetin (CID: 5280343); Superoxide anion radical (CID: 5359597); Superoxide dismutase (CID: 72941490)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estrés Psicológico / Extractos Vegetales / Apoptosis / Estrés Oxidativo / Apocynum / Depresión Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Biomed Pharmacother Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia

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