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Awareness and attitude of the public toward personalized medicine in Korea.
Lee, Iyn-Hyang; Kang, Hye-Young; Suh, Hae Sun; Lee, Sukhyang; Oh, Eun Sil; Jeong, Hotcherl.
Afiliación
  • Lee IH; College of Pharmacy, Yeungnam University, Gyeongbuk-do, South Korea.
  • Kang HY; College of Pharmacy, Yonsei University, Inchon, South Korea.
  • Suh HS; Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Inchon, South Korea.
  • Lee S; College of Pharmacy, Pusan National University, Busan, South Korea.
  • Oh ES; College of Pharmacy, Ajou University, Kyeonggi-do, South Korea.
  • Jeong H; Department of Pharmaceutical Medicine and Regulatory Sciences, Colleges of Medicine and Pharmacy, Yonsei University, Incheon, Korea.
PLoS One ; 13(2): e0192856, 2018.
Article en En | MEDLINE | ID: mdl-29451916
OBJECTIVES: As personalized medicine (PM) is expected to greatly improve health outcomes, efforts have recently been made for its clinical implementation in Korea. We aimed to evaluate public awareness and attitude regarding PM. METHODS: We performed a self-administered questionnaire survey to 703 adults, who participated in the survey on a voluntary basis. The primary outcome measures included public knowledge, attitude, and acceptance of PM. We conducted multinomial multivariate logistic analysis for outcome variables with three response categories and performed multivariate logistic regression analyses for dichotomous outcome variables. RESULTS: Only 28% of participants had knowledge that genetic factors can contribute to inter-individual variations in drug response and the definition of PM (199 out of 702). Higher family income was correlated with greater knowledge concerning PM (OR = 3.76, p = 0.034). A majority of respondents preferred integrated pharmacogenomic testing over drug-specific testing and agreed to inclusion of pharmacogenomic testing in the national health examination (64% and 77%, respectively), but only 51% were willing to pay for it. DISCUSSION: Our results identify the urgent need for public education as well as the potential health disparities in access to PM. This study helps to frame policies for implementing PM in clinical practice.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Conocimientos, Actitudes y Práctica en Salud / Educación del Paciente como Asunto / Medicina de Precisión / Pruebas de Farmacogenómica Tipo de estudio: Prognostic_studies / Qualitative_research Aspecto: Equity_inequality Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Conocimientos, Actitudes y Práctica en Salud / Educación del Paciente como Asunto / Medicina de Precisión / Pruebas de Farmacogenómica Tipo de estudio: Prognostic_studies / Qualitative_research Aspecto: Equity_inequality Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Estados Unidos