Your browser doesn't support javascript.
loading
Muscle Strength and Muscle Endurance During the First Year of Treatment of Polymyositis and Dermatomyositis: A Prospective Study.
Alexanderson, Helene; Regardt, Malin; Ottosson, Christina; Alemo Munters, Li; Dastmalchi, Maryam; Dani, Lara; Lundberg, Ingrid E.
Afiliación
  • Alexanderson H; From the Department of Care Science and Society, Division of Physiotherapy, Karolinska Institutet, Huddinge; Functional Area Occupational Therapy and Physiotherapy, Allied Health Professionals Function, and the Rheumatology Clinic, Karolinska University Hospital, Stockholm; Department of Learning, I
  • Regardt M; H. Alexanderson, PhD, RPT, Department of Care Science and Society, Division of Physiotherapy, Karolinska Institutet, and Functional Area Occupational Therapy and Physiotherapy, Allied Health Professionals Function, Karolinska University Hospital; M. Regardt, PhD, ROT, Functional Area Occupational Th
  • Ottosson C; From the Department of Care Science and Society, Division of Physiotherapy, Karolinska Institutet, Huddinge; Functional Area Occupational Therapy and Physiotherapy, Allied Health Professionals Function, and the Rheumatology Clinic, Karolinska University Hospital, Stockholm; Department of Learning, I
  • Alemo Munters L; H. Alexanderson, PhD, RPT, Department of Care Science and Society, Division of Physiotherapy, Karolinska Institutet, and Functional Area Occupational Therapy and Physiotherapy, Allied Health Professionals Function, Karolinska University Hospital; M. Regardt, PhD, ROT, Functional Area Occupational Th
  • Dastmalchi M; From the Department of Care Science and Society, Division of Physiotherapy, Karolinska Institutet, Huddinge; Functional Area Occupational Therapy and Physiotherapy, Allied Health Professionals Function, and the Rheumatology Clinic, Karolinska University Hospital, Stockholm; Department of Learning, I
  • Dani L; H. Alexanderson, PhD, RPT, Department of Care Science and Society, Division of Physiotherapy, Karolinska Institutet, and Functional Area Occupational Therapy and Physiotherapy, Allied Health Professionals Function, Karolinska University Hospital; M. Regardt, PhD, ROT, Functional Area Occupational Th
  • Lundberg IE; From the Department of Care Science and Society, Division of Physiotherapy, Karolinska Institutet, Huddinge; Functional Area Occupational Therapy and Physiotherapy, Allied Health Professionals Function, and the Rheumatology Clinic, Karolinska University Hospital, Stockholm; Department of Learning, I
J Rheumatol ; 45(4): 538-546, 2018 04.
Article en En | MEDLINE | ID: mdl-29419464
OBJECTIVE: To investigate muscle impairment (isometric and dynamic) and disease activity during the first year after diagnosis of polymyositis (PM) and dermatomyositis (DM), and to study the relationship between muscle impairment, patient-reported health, and disease activity. METHODS: Seventy-two patients enrolled in the Swedish Myositis Register, 2003-2010, were followed prospectively. The Manual Muscle test (MMT-8; isometric muscle strength), the Functional Index of myositis test (FI-2; dynamic, repetitive muscle function), and disease activity (6-item core set) were retrieved at the time of diagnosis, and after 6 and 12 months. Self-reported health (Medical Outcomes Study Short Form-36; SF-36) was retrieved at 12 months. RESULTS: At the time of diagnosis, median (Q1-Q3) for the FI-2 was 27.2% (7.9-60.5%) of maximal score compared to 93.8% (92.5-98.8%) of maximal MMT-8. At 12 months, the FI-2 and the MMT-8 improved to 29.4% (16.5-60.7%; p < 0.05) and 96.1% (88.1-99.4%), respectively (p < 0.01). At 12 months, 45% of patients improved ≥ 20%, and 27% worsened ≥ 20% in FI-2 score, while 10% improved ≥ 20% in MMT-8. Physician's global visual analog scale (VAS), Health Assessment Questionnaire, and creatine phosphokinase levels improved significantly at 12 months (p < 0.05-0.001) while patient's global and extramuscular VAS remained unchanged. The SF-36 physical function correlated strongly with the FI-2 (rs = 0.74; CI 0.55-0.85) and moderately with the MMT (rs = 0.54; CI 0.27-0.73), with lower correlations between muscle function and other SF-36 domains. CONCLUSION: Patients with PM/DM were characterized by impaired dynamic repetitive muscle function (DRMF) that correlated well with patient-reported physical function. Assessment of DRMF adds information regarding muscle impairment in these patients.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Resistencia Física / Dermatomiositis / Fuerza Muscular Tipo de estudio: Diagnostic_studies / Guideline / Observational_studies / Prognostic_studies Aspecto: Patient_preference Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Rheumatol Año: 2018 Tipo del documento: Article Pais de publicación: Canadá
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Resistencia Física / Dermatomiositis / Fuerza Muscular Tipo de estudio: Diagnostic_studies / Guideline / Observational_studies / Prognostic_studies Aspecto: Patient_preference Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Rheumatol Año: 2018 Tipo del documento: Article Pais de publicación: Canadá