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Development and validation of an in-line NIR spectroscopic method for continuous blend potency determination in the feed frame of a tablet press.
De Leersnyder, Fien; Peeters, Elisabeth; Djalabi, Hasna; Vanhoorne, Valérie; Van Snick, Bernd; Hong, Ke; Hammond, Stephen; Liu, Angela Yang; Ziemons, Eric; Vervaet, Chris; De Beer, Thomas.
Afiliación
  • De Leersnyder F; Laboratory Process Analytical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
  • Peeters E; SPECTech Group, Analytical R&D, Worldwide Research and Development, Pfizer Inc., 280 Shennecossett Rd, Groton, USA.
  • Djalabi H; Laboratory Process Analytical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
  • Vanhoorne V; Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
  • Van Snick B; Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
  • Hong K; Advanced Manufacturing Technology Group, Pfizer Global Supply, Pfizer Inc., 100 US-206, Peapack, USA.
  • Hammond S; Process Analytical Sciences Group, Pfizer Global Supply, Pfizer Inc., 100 US-206, Peapack, USA.
  • Liu AY; SPECTech Group, Analytical R&D, Worldwide Research and Development, Pfizer Inc., 280 Shennecossett Rd, Groton, USA.
  • Ziemons E; CIRM, Laboratory of Analytical Chemistry, Department of Pharmacy, University of Liege (ULg), 1 Avenue de l'Hôpital, B36, 4000, Liège, Belgium.
  • Vervaet C; Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
  • De Beer T; Laboratory Process Analytical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium. Electronic address: Thomas.debeer@ugent.be.
J Pharm Biomed Anal ; 151: 274-283, 2018 Mar 20.
Article en En | MEDLINE | ID: mdl-29413975
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Comprimidos / Tecnología Farmacéutica / Espectroscopía Infrarroja Corta / Composición de Medicamentos / Modelos Químicos Tipo de estudio: Prognostic_studies Idioma: En Revista: J Pharm Biomed Anal Año: 2018 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Comprimidos / Tecnología Farmacéutica / Espectroscopía Infrarroja Corta / Composición de Medicamentos / Modelos Químicos Tipo de estudio: Prognostic_studies Idioma: En Revista: J Pharm Biomed Anal Año: 2018 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Reino Unido