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Pro-metastatic activity of AGR2 interrupts angiogenesis target bevacizumab efficiency via direct interaction with VEGFA and activation of NF-κB pathway.
Jia, Mengqi; Guo, Yanxia; Zhu, Deyu; Zhang, Nianzhao; Li, Lin; Jiang, Jin; Dong, Yiwen; Xu, Qingqing; Zhang, Xiulei; Wang, Meijuan; Yu, Haina; Wang, Fang; Tian, Keli; Zhang, Jinsan; Young, Charles Y F; Lou, Hongxiang; Yuan, Huiqing.
Afiliación
  • Jia M; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
  • Guo Y; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
  • Zhu D; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
  • Zhang N; Department of Urology, Qilu Hospital of Shandong University, Jinan, China.
  • Li L; Department of Nature Product Chemistry, Key Laboratory of Chemical Biology of Ministry of Education, Shandong University School of Pharmaceutical Sciences, Jinan, China.
  • Jiang J; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
  • Dong Y; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
  • Xu Q; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
  • Zhang X; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
  • Wang M; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
  • Yu H; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
  • Wang F; Center for Stem Cell and Regenerative Medicine, The Second Hospital of Shandong University, Jinan, China.
  • Tian K; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
  • Zhang J; School of Pharmaceutical Sciences and Center for Precision Medicine, The First Affiliated Hospital, Wenzhou Medical University, China; Institute of Life Sciences, Wenzhou University, Wenzhou, Zhejiang, China.
  • Young CYF; Department of Urology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, MN, USA.
  • Lou H; Department of Nature Product Chemistry, Key Laboratory of Chemical Biology of Ministry of Education, Shandong University School of Pharmaceutical Sciences, Jinan, China.
  • Yuan H; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China. Electronic address: lyuanhq@sdu.edu.cn.
Biochim Biophys Acta Mol Basis Dis ; 1864(5 Pt A): 1622-1633, 2018 May.
Article en En | MEDLINE | ID: mdl-29410027
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Transducción de Señal / Proteínas / Factor A de Crecimiento Endotelial Vascular / Factor de Transcripción ReIA / Bevacizumab / Proteínas de Neoplasias / Neovascularización Patológica Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Biochim Biophys Acta Mol Basis Dis Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Transducción de Señal / Proteínas / Factor A de Crecimiento Endotelial Vascular / Factor de Transcripción ReIA / Bevacizumab / Proteínas de Neoplasias / Neovascularización Patológica Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Biochim Biophys Acta Mol Basis Dis Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos