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Part III: Novel checkpoint kinase 2 (Chk2) inhibitors; design, synthesis and biological evaluation of pyrimidine-benzimidazole conjugates.
Galal, Shadia A; Khattab, Muhammad; Shouman, Samia A; Ramadan, Raghda; Kandil, Omaima M; Kandil, Omnia M; Tabll, Ashraf; El Abd, Yasmine S; El-Shenawy, Reem; Attia, Yasmin M; El-Rashedy, Ahmed A; El Diwani, Hoda I.
Afiliación
  • Galal SA; Department of Chemistry of Natural and Microbial Products, Division of Pharmaceutical and Drug Industries, National Research Centre, Cairo, 12622, Egypt. Electronic address: sh12galal@hotmail.com.
  • Khattab M; Department of Chemistry of Natural and Microbial Products, Division of Pharmaceutical and Drug Industries, National Research Centre, Cairo, 12622, Egypt.
  • Shouman SA; Department of Cancer Biology, National Cancer Institute, Cairo University, Egypt.
  • Ramadan R; Radiobiology Unit, Belgian Nuclear Research Center (SCK•CEN), Mol, Belgium; Department of Basic Medical Sciences, Physiology Group, Ghent University, Ghent, Belgium.
  • Kandil OM; Department of Animal Reproduction & Artificial Insemination, Division, of Veterinary Research, National Research Centre, Cairo, 12622, Egypt.
  • Kandil OM; Department of Parasitology, Animal Disease, Division, of Veterinary, National Research Centre, Cairo, 12622, Egypt.
  • Tabll A; Department of Microbial Biotechnology, Division of Genetic Engineering & Biotechnology, National Research Centre, 12622, Cairo, Egypt.
  • El Abd YS; Department of Microbial Biotechnology, Division of Genetic Engineering & Biotechnology, National Research Centre, 12622, Cairo, Egypt.
  • El-Shenawy R; Department of Microbial Biotechnology, Division of Genetic Engineering & Biotechnology, National Research Centre, 12622, Cairo, Egypt.
  • Attia YM; Department of Cancer Biology, National Cancer Institute, Cairo University, Egypt.
  • El-Rashedy AA; Department of Chemistry of Natural and Microbial Products, Division of Pharmaceutical and Drug Industries, National Research Centre, Cairo, 12622, Egypt.
  • El Diwani HI; Department of Chemistry of Natural and Microbial Products, Division of Pharmaceutical and Drug Industries, National Research Centre, Cairo, 12622, Egypt.
Eur J Med Chem ; 146: 687-708, 2018 Feb 25.
Article en En | MEDLINE | ID: mdl-29407991
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirimidinas / Bencimidazoles / Diseño de Fármacos / Inhibidores de Proteínas Quinasas / Quinasa de Punto de Control 2 Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirimidinas / Bencimidazoles / Diseño de Fármacos / Inhibidores de Proteínas Quinasas / Quinasa de Punto de Control 2 Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article Pais de publicación: Francia