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Phytochemical composition, biological potential and enzyme inhibition activity of Scandix pecten-veneris L.
Wahab, Abdul; Jan, Syed Aleem; Rauf, Abdur; Rehman, Zia Ur; Khan, Zahid; Ahmed, Aftab; Syed, Fatima; Safi, Sher Zaman; Khan, Hamayun; Imran, Muhammad.
Afiliación
  • Wahab A; Department of Chemistry, Islamia College University, Peshawar-25120 KP, Pakistan.
  • Jan SA; Biochemistry Section Institute of Chemical Sciences, University of Peshawar, Peshawar-25120 KP, Pakistan.
  • Rauf A; Department of Chemistry, University of Swabi, Anbar-23561 KP, Pakistan.
  • Rehman ZU; Department of Botany, Islamia College University, Peshawar-25120 KP, Pakistan.
  • Khan Z; Biochemistry Section Institute of Chemical Sciences, University of Peshawar, Peshawar-25120 KP, Pakistan.
  • Ahmed A; State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.
  • Syed F; Biochemistry Section Institute of Chemical Sciences, University of Peshawar, Peshawar-25120 KP, Pakistan.
  • Safi SZ; Interdisciplinary Research Center in Biomedical Materials, COMSATS Institute of Information Technology, Lahore-54000, Pakistan.
  • Khan H; Department of Chemistry, Islamia College University, Peshawar-25120 KP, Pakistan.
  • Imran M; Biochemistry Section Institute of Chemical Sciences, University of Peshawar, Peshawar-25120 KP, Pakistan.
J Zhejiang Univ Sci B ; 19(2): 120-129, 2018.
Article en En | MEDLINE | ID: mdl-29405040
OBJECTIVE: Scandix pecten-veneris L. is a less studied wild edible herb and is considered an extinct plant species in many parts of the world. This study was designed to evaluate its phytochemical composition and biological potential of S. pecten-veneris L. METHODS: Phytochemicals including alkaloids, flavonoids, polyphenols, and tannins were determined in extracts of S. pecten-veneris. Antioxidant activity was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH), while reducing power was tested by ferric reducing/antioxidant power (FRAP) assay. Antimicrobial activity against seven bacterial and four fungal strains was evaluated using agar well diffusion assay. Enzymes inhibition study was performed for urease, phosphodiesterase-I, and catalase-II. RESULTS: S. pecten-veneris showed moderate antiradical activity and reducing potential of hydroxyl radicals to about 20% of the initial value. The antioxidant activity of various extracts of S. pecten-veneris showed a linear correlation with total phenolic contents in the order of water>n-butanol>chloroform>ethyl acetate>methanol extracts. S. pecten-veneris leaves showed the highest inhibitory activity against Staphylococcus aureus while the highest antifungal activity was observed against Candida albicans. The plant extract was most potent against urease enzymes but showed moderate activity against phosphodiestrase-I and carbonic anhydrase-II. CONCLUSIONS: Our data demonstrate that in addition to its culinary uses, S. pecten-veneris has good medicinal potential and hence could be used for treating some specific health ailments.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plantas Comestibles / Extractos Vegetales / Apiaceae / Inhibidores Enzimáticos / Fitoquímicos Límite: Animals Idioma: En Revista: J Zhejiang Univ Sci B Asunto de la revista: BIOLOGIA / MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: Pakistán Pais de publicación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plantas Comestibles / Extractos Vegetales / Apiaceae / Inhibidores Enzimáticos / Fitoquímicos Límite: Animals Idioma: En Revista: J Zhejiang Univ Sci B Asunto de la revista: BIOLOGIA / MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: Pakistán Pais de publicación: China