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Mutant torsinA in the heterozygous DYT1 state compromises HSV propagation in infected neurons and fibroblasts.
György, Bence; Cruz, Lilian; Yellen, David; Aufiero, Massimo; Alland, Isabel; Zhang, Xuan; Ericsson, Maria; Fraefel, Cornel; Li, Yu-Ching; Takeda, Shuko; Hyman, Bradley T; Breakefield, Xandra O.
Afiliación
  • György B; Molecular Neurogenetics Unit, Department of Neurology and Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital and Program in Neuroscience, Harvard Medical School, Boston, MA, 02114, USA.
  • Cruz L; Department of Neurobiology, Harvard Medical School, Boston, MA, 02115, USA.
  • Yellen D; Molecular Neurogenetics Unit, Department of Neurology and Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital and Program in Neuroscience, Harvard Medical School, Boston, MA, 02114, USA.
  • Aufiero M; Molecular Neurogenetics Unit, Department of Neurology and Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital and Program in Neuroscience, Harvard Medical School, Boston, MA, 02114, USA.
  • Alland I; Molecular Neurogenetics Unit, Department of Neurology and Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital and Program in Neuroscience, Harvard Medical School, Boston, MA, 02114, USA.
  • Zhang X; Molecular Neurogenetics Unit, Department of Neurology and Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital and Program in Neuroscience, Harvard Medical School, Boston, MA, 02114, USA.
  • Ericsson M; Molecular Neurogenetics Unit, Department of Neurology and Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital and Program in Neuroscience, Harvard Medical School, Boston, MA, 02114, USA.
  • Fraefel C; Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA.
  • Li YC; Institute of Virology, University of Zurich, Zurich, 8057, Switzerland.
  • Takeda S; Department of Neurology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
  • Hyman BT; Department of Neurology, Massachusetts General Hospital, Massachusetts General Institute of Neurodegenerative Diseases (MIND), Charlestown, MA, 02129, USA.
  • Breakefield XO; Massachusetts Alzheimer Disease Research Center, Charlestown, MA, 02129, USA.
Sci Rep ; 8(1): 2324, 2018 02 02.
Article en En | MEDLINE | ID: mdl-29396398

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Replicación Viral / Herpesvirus Humano 1 / Chaperonas Moleculares / Interacciones Huésped-Patógeno / Fibroblastos / Heterocigoto / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Replicación Viral / Herpesvirus Humano 1 / Chaperonas Moleculares / Interacciones Huésped-Patógeno / Fibroblastos / Heterocigoto / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido