ß-arrestin 2 attenuates lipopolysaccharide-induced liver injury <i>via</i> inhibition of TLR4/NF-&#954;B signaling pathway-mediated inflammation in mice.

Jiang, Meng-Ping; Xu, Chun; Guo, Yun-Wei; Luo, Qian-Jiang; Li, Lin; Liu, Hui-Ling; Jiang, Jie; Chen, Hui-Xin; Wei, Xiu-Qing

ß-arrestin 2 attenuates lipopolysaccharide-induced liver injury via inhibition of TLR4/NF-κB signaling pathway-mediated inflammation in mice.

Jiang, Meng-Ping; Xu, Chun; Guo, Yun-Wei; Luo, Qian-Jiang; Li, Lin; Liu, Hui-Ling; Jiang, Jie; Chen, Hui-Xin; Wei, Xiu-Qing.

Afiliación

Jiang MP; Department of Digestive Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China.
Xu C; Department of Digestive Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China.
Guo YW; Department of Digestive Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China.
Luo QJ; Department of Digestive Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China.
Li L; Department of Digestive Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China.
Liu HL; Department of Digestive Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China.
Jiang J; Department of Digestive Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China.
Chen HX; Department of Digestive Diseases, Huizhou Municipal Center Hospital, Huizhou 516002, Guangdong Province, China.
Wei XQ; Department of Digestive Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China. weixq@mail.sysu.edu.cn.

World J Gastroenterol ; 24(2): 216-225, 2018 Jan 14.

Article en En | MEDLINE | ID: mdl-29375207

Asunto(s)

Enfermedad Hepática Inducida por Sustancias y Drogas/prevención & control; Lipopolisacáridos; Hígado/metabolismo; FN-kappa B/metabolismo; Transducción de Señal; Receptor Toll-Like 4/metabolismo; Arrestina beta 2/metabolismo; Animales; Enfermedad Hepática Inducida por Sustancias y Drogas/etiología; Enfermedad Hepática Inducida por Sustancias y Drogas/metabolismo; Enfermedad Hepática Inducida por Sustancias y Drogas/patología; Citocinas/metabolismo; Modelos Animales de Enfermedad; Mediadores de Inflamación/metabolismo; Hígado/patología; Masculino; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Inhibidor NF-kappaB alfa/metabolismo; Fosforilación; Células RAW 264.7; Factor de Transcripción ReIA/metabolismo; Arrestina beta 2/deficiencia; Arrestina beta 2/genética

Palabras clave

Lipopolysaccharide; Liver injury; Pro-inflammatory cytokines; TLR4/NF-κB signaling pathway; ß-arrestin 2

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Lipopolisacáridos / FN-kappa B / Receptor Toll-Like 4 / Enfermedad Hepática Inducida por Sustancias y Drogas / Arrestina beta 2 / Hígado Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: World J Gastroenterol Asunto de la revista: GASTROENTEROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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