Hitchhiking in space: Ancestry in adapting, spatially extended populations.
Evolution
; 72(4): 722-734, 2018 04.
Article
en En
| MEDLINE
| ID: mdl-29360179
Selective sweeps reduce neutral genetic diversity. In sexual populations, this "hitchhiking" effect is thought to be limited to the local genomic region of the sweeping allele. While this is true in panmictic populations, we find that in spatially extended populations the combined effects of many unlinked sweeps can affect patterns of ancestry (and therefore neutral genetic diversity) across the whole genome. Even low rates of sweeps can be enough to skew the spatial locations of ancestors such that neutral mutations that occur in an individual living outside a small region in the center of the range have virtually no chance of fixing in the population. The fact that nearly all ancestry rapidly traces back to a small spatial region also means that relatedness between individuals falls off very slowly as a function of the spatial distance between them.
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Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Selección Genética
/
Variación Genética
/
Evolución Molecular
/
Modelos Genéticos
Idioma:
En
Revista:
Evolution
Año:
2018
Tipo del documento:
Article
Pais de publicación:
Estados Unidos