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Enediyne-Comprising Amino Aldehydes in the Passerini Reaction.
Glavas, Mladena; Gredicak, Matija; Jeric, Ivanka.
Afiliación
  • Glavas M; Division of Organic Chemistry and Biochemistry , Ruder Boskovic Institute , Bijenicka cesta 54 , 10000 Zagreb , Croatia.
  • Gredicak M; Division of Organic Chemistry and Biochemistry , Ruder Boskovic Institute , Bijenicka cesta 54 , 10000 Zagreb , Croatia.
  • Jeric I; Division of Organic Chemistry and Biochemistry , Ruder Boskovic Institute , Bijenicka cesta 54 , 10000 Zagreb , Croatia.
ACS Comb Sci ; 20(3): 151-155, 2018 03 12.
Article en En | MEDLINE | ID: mdl-29338199
Multicomponent reactions represent a highly efficient approach to a broad spectrum of structurally diverse compounds starting from simple and affordable compounds. A focused library of tweezers-like compounds is prepared by employing the multicomponent Passerini reaction comprising enediyne-derived amino aldehydes. The reaction proceeds under mild conditions yielding Passerini products in good to excellent yields. Postcondensation modifications of Passerini products are demonstrated through a simple deprotection/coupling approach comprising amino functionality, furnishing enediyne cores with highly decorated arms.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aldehídos / Enediinos / Bibliotecas de Moléculas Pequeñas Idioma: En Revista: ACS Comb Sci Año: 2018 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aldehídos / Enediinos / Bibliotecas de Moléculas Pequeñas Idioma: En Revista: ACS Comb Sci Año: 2018 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: Estados Unidos