Advantages of the Alpha-lipoic Acid Association with Chlorpromazine in a Model of Schizophrenia Induced by Ketamine in Rats: Behavioral and Oxidative Stress evidences.

Sampaio, Luis Rafael Leite; Cysne Filho, Francisco Maurício Sales; de Almeida, Jamily Cunha; Diniz, Danilo Dos Santos; Patrocínio, Cláudio Felipe Vasconcelos; de Sousa, Caren Nádia Soares; Patrocínio, Manoel Cláudio Azevedo; Macêdo, Danielle; Vasconcelos, Silvânia Maria Mendes

Sampaio, Luis Rafael Leite; Cysne Filho, Francisco Maurício Sales; de Almeida, Jamily Cunha; Diniz, Danilo Dos Santos; Patrocínio, Cláudio Felipe Vasconcelos; de Sousa, Caren Nádia Soares; Patrocínio, Manoel Cláudio Azevedo; Macêdo, Danielle; Vasconcelos, Silvânia Maria Mendes.

Afiliación

Sampaio LRL; Neuropsychopharmacology Laboratory, Department of Physiology and Pharmacology, Drug Research and Development Center, Faculty of Medicine, Federal University of Ceará Fortaleza, CE, Brazil; Center of Biological and Health Sciences, Regional University of Cariri Cariri, CE, Brazil.
Cysne Filho FMS; University of Fortaleza Fortaleza, CE, Brazil.
de Almeida JC; University of Fortaleza Fortaleza, CE, Brazil.
Diniz DDS; Neuropsychopharmacology Laboratory, Department of Physiology and Pharmacology, Drug Research and Development Center, Faculty of Medicine, Federal University of Ceará Fortaleza, CE, Brazil.
Patrocínio CFV; School of Medicine, University Center Christus-Unichristus Fortaleza, CE, Brazil.
de Sousa CNS; Neuropsychopharmacology Laboratory, Department of Physiology and Pharmacology, Drug Research and Development Center, Faculty of Medicine, Federal University of Ceará Fortaleza, CE, Brazil.
Patrocínio MCA; School of Medicine, University Center Christus-Unichristus Fortaleza, CE, Brazil.
Macêdo D; Neuropsychopharmacology Laboratory, Department of Physiology and Pharmacology, Drug Research and Development Center, Faculty of Medicine, Federal University of Ceará Fortaleza, CE, Brazil.
Vasconcelos SMM; Neuropsychopharmacology Laboratory, Department of Physiology and Pharmacology, Drug Research and Development Center, Faculty of Medicine, Federal University of Ceará Fortaleza, CE, Brazil. Electronic address: silvania@pq.cnpq.br.

Neuroscience ; 373: 72-81, 2018 03 01.

Article en En | MEDLINE | ID: mdl-29337238

Asunto(s)

Antioxidantes/farmacología; Antipsicóticos/farmacología; Clorpromazina/farmacología; Esquizofrenia/tratamiento farmacológico; Ácido Tióctico/farmacología; Animales; Modelos Animales de Enfermedad; Quimioterapia Combinada; Hipocampo/efectos de los fármacos; Hipocampo/metabolismo; Ketamina; Peroxidación de Lípido/efectos de los fármacos; Peroxidación de Lípido/fisiología; Masculino; Memoria a Corto Plazo/efectos de los fármacos; Actividad Motora/efectos de los fármacos; Nitrilos/metabolismo; Estrés Oxidativo/efectos de los fármacos; Estrés Oxidativo/fisiología; Inhibición Prepulso/efectos de los fármacos; Distribución Aleatoria; Ratas Wistar; Esquizofrenia/metabolismo

Palabras clave

Hippocampus; alpha-lipoic acid; chlorpromazine; ketamine; oxidative stress; schizophrenia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquizofrenia / Antipsicóticos / Clorpromazina / Ácido Tióctico / Antioxidantes Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Neuroscience Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos

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