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[Role of genetic markers in personalization of anti-angiogenic therapy in patients with exudative age-related macular degeneration]. / Rol' geneticheskikh markerov v personalizatsii antiangiogennoi terapii ékssudativnoi formy vozrastnoi makuliarnoi degeneratsii.
Moshetova, L K; Sychev, D A; Osmanova, E R; Turkina, K I.
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  • Moshetova LK; Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation, 2/1 Barrikadnaya St., Moscow, Russian Federation, 123995.
  • Sychev DA; Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation, 2/1 Barrikadnaya St., Moscow, Russian Federation, 123995.
  • Osmanova ER; Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation, 2/1 Barrikadnaya St., Moscow, Russian Federation, 123995.
  • Turkina KI; Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation, 2/1 Barrikadnaya St., Moscow, Russian Federation, 123995.
Vestn Oftalmol ; 133(6): 120-125, 2017.
Article en Ru | MEDLINE | ID: mdl-29319678
The review presents data of clinical and pharmacogenetic research by Russian and foreign authors conducted within the last three years on the effectiveness of anti-angiogenic treatment against wet age-related macular degeneration (AMD). Scientific results on the association between angiogenesis-related gene polymorphisms responsible for predisposition to AMD on the one hand and a positive response to anti-VEGF therapy on the other are presented. Particular attention is paid to the main regulator of angiogenesis - the VEGF-A gene.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de la Angiogénesis / Factor A de Crecimiento Endotelial Vascular / Degeneración Macular Tipo de estudio: Diagnostic_studies Límite: Aged / Humans Idioma: Ru Revista: Vestn Oftalmol Año: 2017 Tipo del documento: Article Pais de publicación: Rusia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de la Angiogénesis / Factor A de Crecimiento Endotelial Vascular / Degeneración Macular Tipo de estudio: Diagnostic_studies Límite: Aged / Humans Idioma: Ru Revista: Vestn Oftalmol Año: 2017 Tipo del documento: Article Pais de publicación: Rusia