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Extensively drug-resistant ArmA-producing Acinetobacter baumannii in an Italian intensive care unit.
Caio, Carla; Maugeri, Gaetano; Zingali, Tiziana; Gona, Floriana; Stefani, Stefania; Mezzatesta, Maria Lina.
Afiliación
  • Caio C; Department of Biomedical and Biotechnological Sciences, section of Microbiology, University of Catania, Italy.
  • Maugeri G; Department of Biomedical and Biotechnological Sciences, section of Microbiology, University of Catania, Italy.
  • Zingali T; Department of Biomedical and Biotechnological Sciences, section of Microbiology, University of Catania, Italy.
  • Gona F; Department of Laboratory Medicine and Advanced Biotechnologies, IRCCS-ISMETT (Istituto Mediterraneo dei Trapianti e Terapie ad Alta Specializzazione), Palermo, Italy.
  • Stefani S; Department of Biomedical and Biotechnological Sciences, section of Microbiology, University of Catania, Italy.
  • Mezzatesta ML; Department of Biomedical and Biotechnological Sciences, section of Microbiology, University of Catania, Italy.
New Microbiol ; 41(2): 159-161, 2018 Apr.
Article en En | MEDLINE | ID: mdl-29313866
We describe the spread of 12 carbapenem-resistant Acinetobacter baumannii isolates in hospitalized patients. All strains showed an extensively drug-resistant phenotype and high-level of aminoglycoside resistance, harboring the ArmA gene and blaoxa-23 downstream of ISAba1 (transposon Tn2008 arrangement) where both were located on the chromosome. These strains carry a class 1 integron containing the gene cassette aacA4-catB8-aadA1. Molecular analysis revealed that all isolates belonged to the same sequence type (ST) 2 clone. The spread of ArmA-producing A. baumannii strains limit the treatment options showing the dramatic situation which requires novel therapies to limit high mortality rates.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Infecciones por Acinetobacter / Farmacorresistencia Bacteriana Múltiple / Acinetobacter baumannii / Antibacterianos Límite: Humans País/Región como asunto: Europa Idioma: En Revista: New Microbiol Asunto de la revista: MICROBIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia
Buscar en Google
Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Infecciones por Acinetobacter / Farmacorresistencia Bacteriana Múltiple / Acinetobacter baumannii / Antibacterianos Límite: Humans País/Región como asunto: Europa Idioma: En Revista: New Microbiol Asunto de la revista: MICROBIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia