Novel, Anti-hTNF-&#945; Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development.

Ubah, Obinna C; Steven, John; Kovaleva, Marina; Ferguson, Laura; Barelle, Charlotte; Porter, Andrew J R; Barelle, Caroline J

Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development.

Ubah, Obinna C; Steven, John; Kovaleva, Marina; Ferguson, Laura; Barelle, Charlotte; Porter, Andrew J R; Barelle, Caroline J.

Afiliación

Ubah OC; Elasmogen Ltd., Aberdeen, Scotland.
Steven J; Elasmogen Ltd., Aberdeen, Scotland.
Kovaleva M; Elasmogen Ltd., Aberdeen, Scotland.
Ferguson L; Elasmogen Ltd., Aberdeen, Scotland.
Barelle C; Elasmogen Ltd., Aberdeen, Scotland.
Porter AJR; Elasmogen Ltd., Aberdeen, Scotland.
Barelle CJ; Scottish Biologics Facility, Institute of Medical Sciences, University of Aberdeen, Aberdeen, Scotland.

Front Immunol ; 8: 1780, 2017.

Article en En | MEDLINE | ID: mdl-29312310

Palabras clave

anti-TNF biologics; bi-paratopic/bi-specific binding domain; chronic inflammation; cytokine neutralization; phage display; shark IgNAR; tumor necrosis factor-α; variable new antigen receptor

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Immunol Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Suiza

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