Your browser doesn't support javascript.
loading
Home Exercise Training Improves Exercise Capacity in Cirrhosis Patients: Role of Exercise Adherence.
Kruger, Calvin; McNeely, Margaret L; Bailey, Robert J; Yavari, Milad; Abraldes, Juan G; Carbonneau, Michelle; Newnham, Kim; DenHeyer, Vanessa; Ma, Mang; Thompson, Richard; Paterson, Ian; Haykowsky, Mark J; Tandon, Puneeta.
Afiliación
  • Kruger C; Cirrhosis Care Clinic, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
  • McNeely ML; Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB, Canada.
  • Bailey RJ; Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB, Canada.
  • Yavari M; Liver Health Clinic, Royal Alexandra Hospital, Edmonton, AB, Canada.
  • Abraldes JG; Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB, Canada.
  • Carbonneau M; Cirrhosis Care Clinic, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
  • Newnham K; Cirrhosis Care Clinic, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
  • DenHeyer V; Cirrhosis Care Clinic, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
  • Ma M; Cirrhosis Care Clinic, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
  • Thompson R; Cirrhosis Care Clinic, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
  • Paterson I; Department of Biomedical Engineering, University of Alberta, Edmonton, AB, Canada.
  • Haykowsky MJ; Division of Cardiology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
  • Tandon P; College of Nursing and Health Innovation, University of Texas at Arlington, Arlington, Texas, USA.
Sci Rep ; 8(1): 99, 2018 01 08.
Article en En | MEDLINE | ID: mdl-29311671
Cirrhosis patients have reduced peak aerobic power (peak VO2) that is associated with reduced survival. Supervised exercise training increases exercise tolerance. The effect of home-based exercise training (HET) in cirrhosis is unknown. The objective was to evaluate the safety and efficacy of 8 weeks of HET on peak VO2, 6-minute walk distance (6MWD), muscle mass, and quality of life in cirrhosis. Random assignment to 8 weeks of HET (moderate to high intensity cycling exercise, 3 days/week) or usual care. Exercise adherence defined as completing ≥80% training sessions. Paired t-tests and analysis of covariance used for comparisons. Forty patients enrolled: 58% male, mean age 57 y, 70% Child Pugh-A. Between group increases in peak VO2 (1.7, 95% CI: -0.33 to 3.7 ml/kg/min, p = 0.09) and 6MWD (33.7, 95% CI: 5.1 to 62.4 m, p = 0.02) were greater after HET versus usual care. Improvements even more marked in adherent subjects for peak VO2 (2.8, 95% CI: 0.5-5.2 mL/kg/min, p = 0.02) and 6MWD (46.4, 95% CI: 12.4-80.5 m, p = 0.009). No adverse events occurred during testing or HET. Eight weeks of HET is a safe and effective intervention to improve exercise capacity in cirrhosis, with maximal benefits occurring in those who complete ≥80% of the program.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ejercicio Físico / Tolerancia al Ejercicio / Cirrosis Hepática Tipo de estudio: Clinical_trials / Diagnostic_studies Aspecto: Patient_preference Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ejercicio Físico / Tolerancia al Ejercicio / Cirrosis Hepática Tipo de estudio: Clinical_trials / Diagnostic_studies Aspecto: Patient_preference Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido