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Recent progress in understanding the mechanisms of Leydig cell differentiation.
Inoue, Miki; Baba, Takashi; Morohashi, Ken-Ichirou.
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  • Inoue M; Division of Molecular Life Sciences, Graduate School of Systems Life Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan.
  • Baba T; Division of Molecular Life Sciences, Graduate School of Systems Life Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan; Department of Molecular Biology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan.
  • Morohashi KI; Division of Molecular Life Sciences, Graduate School of Systems Life Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan; Department of Molecular Biology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan. Electronic address: moro@cell.med.kyushu-u.ac.jp.
Mol Cell Endocrinol ; 468: 39-46, 2018 06 15.
Article en En | MEDLINE | ID: mdl-29309805
Leydig cells in fetal and adult testes play pivotal roles in eliciting male characteristics by producing androgen. Although numerous studies of Leydig cells have been performed, the mechanisms for differentiation of the two cell types (fetal Leydig and adult Leydig cells), their developmental and functional relationship, and their differential characteristics remain largely unclear. Based on recent technical progress in genome-wide analysis and in vitro investigation, novel and fascinating observations concerning the issues above have been obtained. Focusing on fetal and adult Leydig cells, this review summarizes the recent progress that has advanced our understanding of the cells.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diferenciación Celular / Células Intersticiales del Testículo Límite: Animals / Humans / Male Idioma: En Revista: Mol Cell Endocrinol Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Irlanda
Texto completo
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Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diferenciación Celular / Células Intersticiales del Testículo Límite: Animals / Humans / Male Idioma: En Revista: Mol Cell Endocrinol Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Irlanda