In vitro and in vivo effects of selected fibers on the pharmacokinetics of orally administered carbamazepine: Possible interaction between therapeutic drugs and semisolid enteral nutrients.

Nagai, Katsuhito; Omotani, Sachiko; Otani, Miki; Sasatani, Moe; Takashima, Takahiro; Hatsuda, Yasutoshi; Mukai, Junji; Myotoku, Michiaki

In vitro and in vivo effects of selected fibers on the pharmacokinetics of orally administered carbamazepine: Possible interaction between therapeutic drugs and semisolid enteral nutrients.

Nagai, Katsuhito; Omotani, Sachiko; Otani, Miki; Sasatani, Moe; Takashima, Takahiro; Hatsuda, Yasutoshi; Mukai, Junji; Myotoku, Michiaki.

Afiliación

Nagai K; Laboratory of Practical Pharmacy and Pharmaceutical Care, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Japan.
Omotani S; Laboratory of Practical Pharmacy and Pharmaceutical Care, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Japan.
Otani M; Laboratory of Practical Pharmacy and Pharmaceutical Care, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Japan.
Sasatani M; Laboratory of Practical Pharmacy and Pharmaceutical Care, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Japan.
Takashima T; Laboratory of Practical Pharmacy and Pharmaceutical Care, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Japan.
Hatsuda Y; Laboratory of Practical Pharmacy and Pharmaceutical Care, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Japan.
Mukai J; Laboratory of Practical Pharmacy and Pharmaceutical Care, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Japan.
Myotoku M; Laboratory of Practical Pharmacy and Pharmaceutical Care, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Japan. Electronic address: myoutom@osaka-ohtani.ac.jp.

Nutrition ; 46: 44-47, 2018 02.

Article en En | MEDLINE | ID: mdl-29290355

Asunto(s)

Carbamazepina/farmacocinética; Fibras de la Dieta/farmacología; Nutrientes/farmacología; Adsorción; Animales; Carbamazepina/administración & dosificación; Interacciones Farmacológicas; Galactanos/química; Masculino; Mananos/química; Nutrientes/química; Gomas de Plantas/química; Polisacáridos Bacterianos/química; Ratas; Ratas Sprague-Dawley; Viscosidad

Palabras clave

Adsorption; Carbamazepine; Fiber; Pharmacokinetics; Semisolid enteral nutrient

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carbamazepina / Fibras de la Dieta / Nutrientes Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nutrition Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

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