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Rational Design, Binding Studies, and Crystal-Structure Evaluation of the First Ligand Targeting the Dimerization Interface of the 14-3-3ζ Adapter Protein.
Ehlers, Martin; Grad, Jean-Noël; Mittal, Sumit; Bier, David; Mertel, Marcel; Ohl, Ludwig; Bartel, Maria; Briels, Jeroen; Heimann, Marius; Ottmann, Christian; Sanchez-Garcia, Elsa; Hoffmann, Daniel; Schmuck, Carsten.
Afiliación
  • Ehlers M; Institute of Organic Chemistry, University of Duisburg-Essen (Germany), Universitätsstrasse 7, 45141, Essen, Germany.
  • Grad JN; Computational Biochemistry, University of Duisburg-Essen, Universitätsstrasse 2, 45141, Essen, Germany.
  • Mittal S; Computational Biochemistry, University of Duisburg-Essen, Universitätsstrasse 2, 45141, Essen, Germany.
  • Bier D; Department of Chemistry, University of Duisburg-Essen, Universitätsstrasse 7, 45141, Essen, Germany.
  • Mertel M; Institute of Organic Chemistry, University of Duisburg-Essen (Germany), Universitätsstrasse 7, 45141, Essen, Germany.
  • Ohl L; Computational Biochemistry, University of Duisburg-Essen, Universitätsstrasse 2, 45141, Essen, Germany.
  • Bartel M; Department of Chemistry, University of Duisburg-Essen, Universitätsstrasse 7, 45141, Essen, Germany.
  • Briels J; Department of Biomedical Engineering and, Institute for Complex Molecular Systems, Technische Universiteit Eindhoven, P. O. Box 513, 5600 MB, Eindhoven, Netherlands.
  • Heimann M; Department of Chemistry, University of Duisburg-Essen, Universitätsstrasse 7, 45141, Essen, Germany.
  • Ottmann C; Department of Biomedical Engineering and, Institute for Complex Molecular Systems, Technische Universiteit Eindhoven, P. O. Box 513, 5600 MB, Eindhoven, Netherlands.
  • Sanchez-Garcia E; Institute of Organic Chemistry, University of Duisburg-Essen (Germany), Universitätsstrasse 7, 45141, Essen, Germany.
  • Hoffmann D; Department of Chemistry, University of Duisburg-Essen, Universitätsstrasse 7, 45141, Essen, Germany.
  • Schmuck C; Department of Biomedical Engineering and, Institute for Complex Molecular Systems, Technische Universiteit Eindhoven, P. O. Box 513, 5600 MB, Eindhoven, Netherlands.
Chembiochem ; 19(6): 591-595, 2018 03 16.
Article en En | MEDLINE | ID: mdl-29282826
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos / Diseño de Fármacos / Proteínas 14-3-3 / Bibliotecas de Moléculas Pequeñas Límite: Humans Idioma: En Revista: Chembiochem Asunto de la revista: BIOQUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos / Diseño de Fármacos / Proteínas 14-3-3 / Bibliotecas de Moléculas Pequeñas Límite: Humans Idioma: En Revista: Chembiochem Asunto de la revista: BIOQUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania