Anti-Ice Nucleation Activities of Adenine and Poly-A Nucleotides.
Biocontrol Sci
; 22(4): 233-237, 2017.
Article
en En
| MEDLINE
| ID: mdl-29279581
ãMost of the ice nucleation activity inhibitor reported so far are compounds processing the hydroxyl group such as the polyphenolic derivative. After examining the anti-ice nucleation activity of the purine base, the highest compound is theophylline, and the activity showed 3.80±0.32â at a final concentration of 0.1 mg/ml. We found that the activity of the adenine which was essential to genome information DNA was higher than that of guanine. After examining effect of adenine concentration, high activity showed 9.1±1.2â and became approximately constant above 0.1 mg/ml. This active rise is a result of effect of concentration under alkaline condition. Therefore after examining effect of pH on the activity of adenine, this activity rose under an alkaline condition. The active rise predicts that an electric charge of adenine is a factor. Among four kinds of nucleotide of 6 bases, poly-A nucleotide was higher and showed 1.33±0.42â at a final concentration of 0.1 mg/ml. This activity of poly-A were proportional to the number of the base. From these results, it was suggested that the poly-A and adenine could be able to be applied to the field to preserve the blood and tissue which differentiated in the generative medicine.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Poli A
/
Adenina
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Biocontrol Sci
Año:
2017
Tipo del documento:
Article
Pais de publicación:
Japón