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Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy.
Potting, Christoph; Crochemore, Christophe; Moretti, Francesca; Nigsch, Florian; Schmidt, Isabel; Manneville, Carole; Carbone, Walter; Knehr, Judith; DeJesus, Rowena; Lindeman, Alicia; Maher, Rob; Russ, Carsten; McAllister, Gregory; Reece-Hoyes, John S; Hoffman, Gregory R; Roma, Guglielmo; Müller, Matthias; Sailer, Andreas W; Helliwell, Stephen B.
Afiliación
  • Potting C; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland.
  • Crochemore C; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland.
  • Moretti F; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland.
  • Nigsch F; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland.
  • Schmidt I; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland.
  • Manneville C; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland.
  • Carbone W; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland.
  • Knehr J; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland.
  • DeJesus R; Novartis Institutes for BioMedical Research, Cambridge, MA 02139.
  • Lindeman A; Novartis Institutes for BioMedical Research, Cambridge, MA 02139.
  • Maher R; Novartis Institutes for BioMedical Research, Cambridge, MA 02139.
  • Russ C; Novartis Institutes for BioMedical Research, Cambridge, MA 02139.
  • McAllister G; Novartis Institutes for BioMedical Research, Cambridge, MA 02139.
  • Reece-Hoyes JS; Novartis Institutes for BioMedical Research, Cambridge, MA 02139.
  • Hoffman GR; Novartis Institutes for BioMedical Research, Cambridge, MA 02139.
  • Roma G; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland.
  • Müller M; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland.
  • Sailer AW; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland.
  • Helliwell SB; Novartis Institutes for BioMedical Research, Basel CH 4002, Switzerland; stephen.helliwell@novartis.com.
Proc Natl Acad Sci U S A ; 115(2): E180-E189, 2018 01 09.
Article en En | MEDLINE | ID: mdl-29269392
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Represoras / Genoma Humano / Regulación de la Expresión Génica / Ubiquitina-Proteína Ligasas / Mitofagia / Sistemas CRISPR-Cas Tipo de estudio: Prognostic_studies Límite: Humans / Newborn Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Represoras / Genoma Humano / Regulación de la Expresión Génica / Ubiquitina-Proteína Ligasas / Mitofagia / Sistemas CRISPR-Cas Tipo de estudio: Prognostic_studies Límite: Humans / Newborn Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Estados Unidos