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Pain management of acute limb trauma patients with intravenous lidocaine in emergency department.
Farahmand, Shervin; Hamrah, Hadid; Arbab, Mona; Sedaghat, Mojtaba; Basir Ghafouri, Hamed; Bagheri-Hariri, Shahram.
Afiliación
  • Farahmand S; Emergency Medicine Department, Tehran University of Medical Sciences, Tehran, Iran.
  • Hamrah H; Tehran University of Medical Sciences, Tehran, Iran.
  • Arbab M; General Surgery Department, Brigham and Women's Hospital, Boston, MA, USA.
  • Sedaghat M; Community Medicine Department, Tehran University of Medical Sciences, Tehran, Iran.
  • Basir Ghafouri H; Trauma and Injury Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Bagheri-Hariri S; Emergency Medicine Department, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: hariri@sina.tums.ac.ir.
Am J Emerg Med ; 36(7): 1231-1235, 2018 Jul.
Article en En | MEDLINE | ID: mdl-29254669
INTRODUCTION: This study was designed to assess the possible superiority of intravenous lidocaine to morphine for pain management. METHODS: This was a randomized double blind controlled superiority trial, carried on in the emergency department (ED). Traumatic patients older than 18-year-old with the complaint of acute pain greater than 4 on a numeric rating scale (NRS) from 0 to 10 on their extremities were eligible. One group received IV lidocaine (1.5 mg/kg), and the other received IV morphine (0.1mg/kg). Pain scores and adverse effects were assessed at 15, 30, 45 and 60 minutes and patients' satisfaction was evaluated two hours later. A minimum pain score reduction of 1.3 from baseline was considered clinically significant. RESULTS: Fifty patients with the mean age of 31.28±8.7 were enrolled (78% male). The demographic characteristics and pain scores of the two groups was similar. The on-arrival mean pain scores in two groups were, lidocaine: 7.9±1.4 and morphine: 8.0±1.4 (p=0.57) and after 1 hour were, lidocaine: 2.28±1.2 and morphine: 3.2±1.7. Although the pain score decreased significantly in both group (p=0.027), there were not any clinically and statistically significant difference between the two groups (p=0.77). Patients' satisfaction with pain management in both groups were almost similar (p=0.49). CONCLUSION: The reduction in pain score using IV lidocaine is not superior to IV morphine in adult ED patients with traumatic limb pain.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Agudo / Anestésicos Locales / Lidocaína Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male Idioma: En Revista: Am J Emerg Med Año: 2018 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Agudo / Anestésicos Locales / Lidocaína Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male Idioma: En Revista: Am J Emerg Med Año: 2018 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos