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The proper use of coronary calcium score and coronary computed tomography angiography for screening asymptomatic patients with cardiovascular risk factors.
Tay, Shee Yen; Chang, Po-Yen; Lao, Wilson T; Lin, Ying Chin; Chung, Yi-Han; Chan, Wing P.
Afiliación
  • Tay SY; Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taipei, 116, Taiwan, Republic of China.
  • Chang PY; Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan, Republic of China.
  • Lao WT; Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taipei, 116, Taiwan, Republic of China.
  • Lin YC; Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan, Republic of China.
  • Chung YH; Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taipei, 116, Taiwan, Republic of China.
  • Chan WP; Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan, Republic of China.
Sci Rep ; 7(1): 17653, 2017 12 15.
Article en En | MEDLINE | ID: mdl-29247160
Early detection and treatment of coronary artery disease (CAD) can reduce incidences of acute myocardial infarction. In this study, we determined the proper use of contributing risk factors and coronary artery calcium score (CACS) when screening asymptomatic patients with coronary arterial stenoses using coronary computed tomography angiography (CCTA). We reviewed 934 consecutive patients who received CACS and CCTA between December 2013 and November 2016. At least one cardiovascular disease risk factor was present in each of the 509 asymptomatic participants. Patients were grouped based on CACS into "zero," "minimal" (0 < CACS ≤ 10), "mild" (10 < CACS ≤ 100), "moderate" (100 < CACS ≤ 400), and "excessive" (CACS > 400). Males over 45 years old with diabetes mellitus and hypertension had a higher risk of significant coronary stenosis. In multivariate analysis, age, sex, hypertension, and diabetes mellitus remained significant predictors of stenosis. A CACS of zero occurred in 227 patients (44.6%). There were no significant differences between the "zero" and "minimal" groups (p = 0.421), but the "mild," "moderate," and "excessive" groups showed correlations with significant coronary stenosis. Age, sex, diabetes mellitus, and hypertension were associated with higher risk of significant coronary stenosis. Asymptomatic patients with CACSs of zero do not require CCTA, and thereby avoid unnecessary radiation exposure.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Calcio / Angiografía Coronaria / Vasos Coronarios / Estenosis Coronaria / Diabetes Mellitus / Angiografía por Tomografía Computarizada / Hipertensión Tipo de estudio: Diagnostic_studies / Etiology_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Calcio / Angiografía Coronaria / Vasos Coronarios / Estenosis Coronaria / Diabetes Mellitus / Angiografía por Tomografía Computarizada / Hipertensión Tipo de estudio: Diagnostic_studies / Etiology_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido