Your browser doesn't support javascript.
loading
Impact of serum albumin levels on long-term all-cause, cardiovascular, and cardiac mortality in patients with first-onset acute myocardial infarction.
Xia, Ming; Zhang, Chi; Gu, Jian; Chen, Jing; Wang, Lin-Chi; Lu, Yan; Huang, Chun-Yan; He, Yong-Ming; Yang, Xiang-Jun.
Afiliación
  • Xia M; Division of Cardiology, First Affiliated Hospital of Soochow University, PR China.
  • Zhang C; Division of Cardiology, First Affiliated Hospital of Soochow University, PR China.
  • Gu J; Division of Cardiology, First Affiliated Hospital of Soochow University, PR China.
  • Chen J; Department of Geriatrics, First Affiliated Hospital of Soochow University, PR China.
  • Wang LC; Suzhou Center for Disease Control and Prevention, PR China.
  • Lu Y; Suzhou Center for Disease Control and Prevention, PR China.
  • Huang CY; Suzhou Center for Disease Control and Prevention, PR China.
  • He YM; Division of Cardiology, First Affiliated Hospital of Soochow University, PR China.
  • Yang XJ; Division of Cardiology, First Affiliated Hospital of Soochow University, PR China. Electronic address: xiangjun_yang218@163.com.
Clin Chim Acta ; 477: 89-93, 2018 Feb.
Article en En | MEDLINE | ID: mdl-29241048
BACKGROUND: To evaluate the association of serum albumin (SA) with long-term all-cause, cardiovascular, and cardiac mortality in patients with first-onset acute myocardial infarction (AMI). METHODS: The cohort study enrolled 2305 patients with first-onset AMI. The median follow-up was of 1088days (3years). Impacts of SA on long-time mortality after AMI were determined using multivariate Cox proportional hazard regression analysis with backward selection. RESULTS: The patients were divided into three categories by SA tertiles (≤3.62, 3.63-4.08, >4.08g/dl). High tertile group was used as reference, the adjusted HRs for all-cause death were 1.21 (P=0.338) and 1.74 (P=0.003) for intermediate and low tertile, respectively (p-for-trend=0.001); The equivalent values for cardiovascular death were 1.13 (P=0.588) and 1.64 (P=0.022), respectively (p-for-trend=0.009); The corresponding values for cardiac death were 1.07 (P=0.806) and 1.59 (P=0.048), respectively (p-for-trend=0.022). Moreover, adjusted HRs per 1-g/dl decrease in SA concentrations were 1.66 (P=0.001) for all-cause death, 1.47 (P=0.024) for cardiovascular death, and 1.61 (P=0.012) for cardiac death. CONCLUSIONS: Low SA level (≤3.62g/dl) on admission was an independent predictor of long-term all-cause, cardiovascular, and cardiac mortality in patients with first-onset AMI. There was a dose-response relationship between decreased SA concentrations and increased long-term all-cause, cardiovascular, and cardiac mortality.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Albúmina Sérica / Enfermedades Cardiovasculares / Causas de Muerte / Infarto del Miocardio Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Chim Acta Año: 2018 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Albúmina Sérica / Enfermedades Cardiovasculares / Causas de Muerte / Infarto del Miocardio Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Chim Acta Año: 2018 Tipo del documento: Article Pais de publicación: Países Bajos