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In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering.
Wu, Qianxin; Ferry, Quentin R V; Baeumler, Toni A; Michaels, Yale S; Vitsios, Dimitrios M; Habib, Omer; Arnold, Roland; Jiang, Xiaowei; Maio, Stefano; Steinkraus, Bruno R; Tapia, Marta; Piazza, Paolo; Xu, Ni; Holländer, Georg A; Milne, Thomas A; Kim, Jin-Soo; Enright, Anton J; Bassett, Andrew R; Fulga, Tudor A.
Afiliación
  • Wu Q; Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DS, UK.
  • Ferry QRV; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
  • Baeumler TA; Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DS, UK.
  • Michaels YS; Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DS, UK.
  • Vitsios DM; Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DS, UK.
  • Habib O; European Molecular Biology Laboratory-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
  • Arnold R; Center for Genome Engineering, Institute for Basic Science (IBS), Seoul, 08826, Republic of Korea.
  • Jiang X; Molecular and Population Genetics Laboratory, Oxford Centre for Cancer Gene Research, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
  • Maio S; Molecular and Population Genetics Laboratory, Oxford Centre for Cancer Gene Research, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
  • Steinkraus BR; Weatherall Institute of Molecular Medicine, Developmental Immunology, University of Oxford, Oxford, OX3 9DS, UK.
  • Tapia M; Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DS, UK.
  • Piazza P; Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, NIHR Oxford Biomedical Research Centre Programme, University of Oxford, Oxford, OX3 9DS, UK.
  • Xu N; Wellcome Trust Centre for Human Genetics, Oxford, OX3 7BN, UK.
  • Holländer GA; Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DS, UK.
  • Milne TA; Weatherall Institute of Molecular Medicine, Developmental Immunology, University of Oxford, Oxford, OX3 9DS, UK.
  • Kim JS; Department of Biomedicine, Laboratory of Paediatric Immunology, University of Basel, CH-4058, Basel, Switzerland.
  • Enright AJ; Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, NIHR Oxford Biomedical Research Centre Programme, University of Oxford, Oxford, OX3 9DS, UK.
  • Bassett AR; Center for Genome Engineering, Institute for Basic Science (IBS), Seoul, 08826, Republic of Korea.
  • Fulga TA; Department of Chemistry, Seoul National University, Seoul, 151-747, Republic of Korea.
Nat Commun ; 8(1): 2109, 2017 12 13.
Article en En | MEDLINE | ID: mdl-29235467
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN / Secuencias Reguladoras de Ácidos Nucleicos / Sistemas CRISPR-Cas / Edición Génica Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN / Secuencias Reguladoras de Ácidos Nucleicos / Sistemas CRISPR-Cas / Edición Génica Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido