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Aging and neurodegeneration are associated with increased mutations in single human neurons.
Lodato, Michael A; Rodin, Rachel E; Bohrson, Craig L; Coulter, Michael E; Barton, Alison R; Kwon, Minseok; Sherman, Maxwell A; Vitzthum, Carl M; Luquette, Lovelace J; Yandava, Chandri N; Yang, Pengwei; Chittenden, Thomas W; Hatem, Nicole E; Ryu, Steven C; Woodworth, Mollie B; Park, Peter J; Walsh, Christopher A.
Afiliación
  • Lodato MA; Division of Genetics and Genomics, Manton Center for Orphan Disease, and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA, USA.
  • Rodin RE; Departments of Neurology and Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Bohrson CL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Coulter ME; Division of Genetics and Genomics, Manton Center for Orphan Disease, and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA, USA.
  • Barton AR; Departments of Neurology and Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Kwon M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Sherman MA; Program in Neuroscience and Harvard/MIT MD-PHD Program, Harvard Medical School, Boston, MA, USA.
  • Vitzthum CM; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Luquette LJ; Division of Genetics and Genomics, Manton Center for Orphan Disease, and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA, USA.
  • Yandava CN; Departments of Neurology and Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Yang P; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Chittenden TW; Program in Neuroscience and Harvard/MIT MD-PHD Program, Harvard Medical School, Boston, MA, USA.
  • Hatem NE; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Ryu SC; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Woodworth MB; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Park PJ; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Walsh CA; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Science ; 359(6375): 555-559, 2018 02 02.
Article en En | MEDLINE | ID: mdl-29217584
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Envejecimiento / Enfermedades Neurodegenerativas / Reparación del ADN / Neurogénesis / Tasa de Mutación Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Science Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Envejecimiento / Enfermedades Neurodegenerativas / Reparación del ADN / Neurogénesis / Tasa de Mutación Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Science Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos